| DiscRep 2058646 · TMA1282136 | Oligo Médic inc. | 5 Pharmaceuticals | Registered | 2025 |
| DISRUPT 2255513 | Owner not listed | 35 Advertising41 Education | Pending | 2023 |
| Descorapid 1177125 · TMA625717 | ANTISEPTICA Dr. Hans-Joachim Molitor GmbH | 5 Pharmaceuticals | Registered | 2004 |
| DECORAPET 2260969 | 1451825 Ontario Limited DBA Bowsers Pet Products Corporation | 12 Vehicles18 Leather20 Furniture+2 | Pending | 2023 |
| DUGRAFT 2175818 · TMA1227074 · design | TITAN STAR TRADING LIMITED | 18 Leather | Registered | 2024 |
| DECOREBAY 2155199 · TMA1207702 | MSHZ International Inc. | 14 Jewellery | Registered | 2023 |
| DISRUPTUS 2140598 · TMA1222187 | FoxMind Group Ltd. | 28 Toys | Registered | 2024 |
| DIYsrupt 2111387 · TMA1243791 | ACCELEREM | 9 Electronics41 Education44 Medical+1 | Registered | 2024 |
| DEKORABLE 2046287 · TMA1275316 · design | an individual | 20 Furniture21 Housewares24 Textiles+1 | Registered | 2024 |
| Disruptor 2034457 · TMA1143654 | 3738 Investments Ltd. | 33 Wine40 Treatment43 Restaurants | Registered | 2022 |
| DEXSORB 1945227 · TMA1192264 | Cyclopure, Inc. | 1 Chemicals | Registered | 2023 |
| DAXCERB 1887476 · TMA1064991 | PFIZER INC. | 5 Pharmaceuticals | Registered | 2019 |
| DSRP 1874003 · TMA1101425 | Frameable Inc. | 41 Education42 Science | Registered | 2021 |
| DISRUPTOR 1869942 · TMA1019623 | NewAgco Inc. | 5 Pharmaceuticals | Registered | 2019 |
| DisruptED 1843247 · TMA1015206 | Information & Communication Technologies Association of Manitoba (ICTAM) | 41 Education | Registered | 2019 |
| DIGRAPHS 1835834 · TMA1075361 | Digraphs Game Corporation | 28 Toys | Registered | 2020 |
| DUOSORB 1820484 · TMA1067782 | CRS HOLDINGS, LLC | 6 Metal | Registered | 2020 |
| DEZARVIC 1795036 · TMA1040984 | Merck Sharp & Dohme LLC | 5 Pharmaceuticals | Registered | 2019 |
| DISRUPTOLOGY 1789325 · TMA1029017 | Investment Planning Counsel Inc. | 36 Finance | Registered | 2019 |
| DISRUPTER 1779762 · TMA971986 | Friction Tool Solutions Inc. | 7 Machines | Registered | 2017 |
| DUKARB 1747010 · TMA1028800 | BORYUNG PHARMACEUTICAL CO. LTD. | 5 Pharmaceuticals | Registered | 2019 |
| DECRAFLEX 1714729 · TMA948099 | PPG Architectural Finishes, Inc. | 2 Paints | Registered | 2016 |
| DISRUPTION 1695181 · TMA1022764 | TBWA Worldwide Inc. a corporation of Delaware | 35 Advertising42 Science | Registered | 2019 |
| DISRUPTOR 1694408 · TMA980613 | Sony Music Entertainment and Adam Alpert Management LLC, a joint venture | 9 Electronics25 Clothing35 Advertising+1 | Registered | 2017 |
| DUOSHARP 1657119 · TMA908641 | ACME UNITED CORPORATION | 8 Hand | Registered | 2015 |