| OPTIMUS360 1584021 · TMA879618 | Marine Canada Acquisition Inc. | 9 Electronics12 Vehicles | Registered | 2014 |
| OPTUM 2032781 · TMA1158087 | BASF Coatings GmbH, a legal entity | 2 Paints | Registered | 2022 |
| OPTUM 1740210 · TMA979836 | Optum, Inc. | 35 Advertising36 Finance37 Construction+5 | Registered | 2017 |
| OPTUM 1740209 · TMA979845 · design | Optum, Inc. | 35 Advertising36 Finance37 Construction+5 | Registered | 2017 |
| OPTUM 1733420 · TMA973645 | CNH Industrial America LLC | 12 Vehicles | Registered | 2017 |
| OPTUMERA 1552844 · TMA901425 · design | Tata Consultancy Services Limited | 9 Electronics16 Paper42 Science | Registered | 2015 |
| OPTUMERA 1551495 · TMA901436 | Tata Consultancy Services Limited | 9 Electronics16 Paper42 Science | Registered | 2015 |
| OPTUM 1537884 · TMA887664 · design | Optum, Inc. | 16 Paper35 Advertising38 Telecommunications+4 | Registered | 2014 |
| OPTUM 1536751 · TMA886380 | Optum, Inc. | 16 Paper35 Advertising38 Telecommunications+4 | Registered | 2014 |
| OPTUM 1107788 · TMA594912 | Optum, Inc. | 16 Paper42 Science44 Medical+1 | Registered | 2003 |
| OPTUM 0821214 · TMA484900 | Optum, Inc. | 44 Medical | Registered | 1997 |
| OPTUM 0781523 · TMA503729 | an individual | 3 Cosmetics5 Pharmaceuticals | Registered | 1998 |
| OPTUM 2231651 · design | Optum, Inc. | 9 Electronics35 Advertising36 Finance+2 | Pending | 2022 |
| OPTIMA3300 2225791 · TMA1252561 | Conair LLC | 9 Electronics | Registered | 2024 |
| OPTIMA3000 1759474 · TMA960183 | Conair LLC | 9 Electronics | Registered | 2017 |
| OPTIMUS 2256065 · TMA1277637 · design | Owner not shown | 34 Tobacco | Registered | 2024 |
| OPDENK 2254873 · TMA1273130 | an individual | 26 Sewing | Registered | 2024 |
| OptaMax 2215632 · TMA1233961 | Opta Group LLC | 1 Chemicals | Registered | 2024 |
| OPTIMALIST 2210401 · TMA1241783 | Opscotch Canada Inc. | 18 Leather21 Housewares24 Textiles+1 | Registered | 2024 |
| Optime 2208243 · TMA1280840 | an individual | 6 Metal7 Machines26 Sewing | Registered | 2025 |
| OptimalRx 2200001 · TMA1238488 | an individual | 44 Medical | Registered | 2024 |
| OBODING 2176924 · TMA1227154 | Guangdong Oubang Trading Co. Ltd. | 21 Housewares | Registered | 2024 |
| OPTOMEDIC 2170124 · TMA1248059 · design | Guangdong OptoMedic Technologies Inc. | 10 Medical | Registered | 2024 |
| Opteinics 2169866 · TMA1232344 | an individual | 9 Electronics35 Advertising42 Science+1 | Registered | 2024 |
| OPTINAND 2161450 · TMA1266838 | Western Digital Technologies, Inc. | 9 Electronics | Registered | 2024 |