| REPLACE 1874744 · TMA1053112 | Edgewell Personal Care Brands, LLC | 8 Hand | Registered | 2019 |
| REPLACE 2316781 · design | REPLACE | 17 Rubber19 Building20 Furniture | Pending | 2023 |
| REFLECTIR 2036750 · TMA1272105 | MSA TECHNOLOGY, LLC | 9 Electronics | Registered | 2024 |
| REPLICA 1944140 · TMA1204525 | MARGIELA | 3 Cosmetics | Registered | 2023 |
| REPLICA 1941111 · TMA1184495 | Replica Inc. | 42 Science | Registered | 2023 |
| REPLICA 1897879 · TMA1082814 · design | 9078-3184 QUÉBEC INC. | 9 Electronics42 Science | Registered | 2020 |
| REPLICAKE 1888848 · TMA1081735 | How to Cake it Inc. | 9 Electronics16 Paper18 Leather+6 | Registered | 2020 |
| REPLAYKIT 1756224 · TMA973110 | Apple Inc. | 9 Electronics | Registered | 2017 |
| REPLICEL 1752615 · TMA1049354 | RepliCel Life Sciences Inc. | 5 Pharmaceuticals10 Medical | Registered | 2019 |
| REPLICA 1751230 · TMA963032 | Integrated Beverage Group LLC | 33 Wine | Registered | 2017 |
| REPLASHADE 1738718 · TMA955024 | Axalta Coating Systems GmbH | 42 Science | Registered | 2016 |
| REPLICART 1448397 · TMA800324 | MESOBLAST LIMITED | 1 Chemicals5 Pharmaceuticals | Registered | 2011 |
| REFLEXIR 1407645 · TMA754485 | Healthy Logix Inc. | 5 Pharmaceuticals16 Paper35 Advertising+1 | Registered | 2009 |
| REPLICATOR 1350128 · TMA783023 | Leviton Manufacturing Co. Inc. a corporation organized and existing under the laws of the State of Delaware | 9 Electronics | Registered | 2010 |
| REPLAGAL 1346340 · TMA719639 · design | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals42 Science44 Medical | Registered | 2008 |
| REPLAGAL 1246415 · TMA652251 · design | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals | Registered | 2005 |
| REPLAGAL 1032514 · TMA633335 | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals | Registered | 2005 |
| REPLICARE 0803684 · TMA508381 | SMITH & NEPHEW, INC. (A DELAWARE CORPORATION) | 5 Pharmaceuticals | Registered | 1999 |
| REPLAYZIQ 2288826 | Replayz Labs Ltd. | 9 Electronics16 Paper35 Advertising+1 | Pending | 2023 |
| RIPPLEX 2255970 · TMA1273166 | Ripple Labs Inc. | 41 Education | Registered | 2024 |
| Refilz 2255124 · TMA1276138 | 1000325553 ONTARIO LIMITED | 4 Oils | Registered | 2024 |
| Rivfloza 2182077 · TMA1212536 | Owner not shown | 5 Pharmaceuticals | Registered | 2023 |
| RIBOWELEC 2175886 · TMA1227086 | Shenzhen Ruibo Electronics Co. Ltd. | 9 Electronics | Registered | 2024 |
| REFLEECE 2171616 · TMA1201973 | an individual | 17 Rubber | Registered | 2023 |
| REVELIST 2162509 · TMA1197130 | Direct Commerce Group, LLC | 21 Housewares | Registered | 2023 |