| REPLICAKE 1888848 · TMA1081735 | How to Cake it Inc. | 9 Electronics16 Paper18 Leather+6 | Registered | 2020 |
| REPLACE 1874744 · TMA1053112 | Edgewell Personal Care Brands, LLC | 8 Hand | Registered | 2019 |
| REPLAGAL 1346340 · TMA719639 · design | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals42 Science44 Medical | Registered | 2008 |
| REPLAGAL 1246415 · TMA652251 · design | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals | Registered | 2005 |
| REPLAGAL 1032514 · TMA633335 | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals | Registered | 2005 |
| REPLACEAIR 0838041 · TMA512985 | SCHUBERT ENVIRONMENTAL EQUIPMENT, INC. | 11 Lighting | Registered | 1999 |
| REPLICARE 0803684 · TMA508381 | SMITH & NEPHEW, INC. (A DELAWARE CORPORATION) | 5 Pharmaceuticals | Registered | 1999 |
| REPLACE 2316781 · design | REPLACE | 17 Rubber19 Building20 Furniture | Pending | 2023 |
| Revoläshion 2008445 | an individual | 35 Advertising41 Education | Pending | 2020 |
| RIPPLEX 2255970 · TMA1273166 | Ripple Labs Inc. | 41 Education | Registered | 2024 |
| Refilz 2255124 · TMA1276138 | 1000325553 ONTARIO LIMITED | 4 Oils | Registered | 2024 |
| Rivfloza 2182077 · TMA1212536 | Owner not shown | 5 Pharmaceuticals | Registered | 2023 |
| RIBOWELEC 2175886 · TMA1227086 | Shenzhen Ruibo Electronics Co. Ltd. | 9 Electronics | Registered | 2024 |
| REFLEECE 2171616 · TMA1201973 | an individual | 17 Rubber | Registered | 2023 |
| REVELIST 2162509 · TMA1197130 | Direct Commerce Group, LLC | 21 Housewares | Registered | 2023 |
| REVOLOX 2140181 · TMA1179567 | Smalley Steel Ring Co. | 6 Metal | Registered | 2023 |
| RFLCT 2093994 · TMA1181626 · design | IdeavationLabs LLC | 3 Cosmetics9 Electronics18 Leather | Registered | 2023 |
| RFLCT 2082915 · TMA1180334 | IdeavationLabs LLC | 3 Cosmetics9 Electronics18 Leather | Registered | 2023 |
| REBLOZYL 2075384 · TMA1117038 · design | Celgene Corporation | 5 Pharmaceuticals | Registered | 2022 |
| Roflex 2053523 · TMA1114688 | KTR Systems GmbH | 7 Machines | Registered | 2021 |
| REBELLIOUS 2045990 · TMA1188127 | Kobrand Corporation | 33 Wine | Registered | 2023 |
| REBELLIOUS 2045988 · TMA1198518 · design | Kobrand Corporation | 33 Wine | Registered | 2023 |
| REFLECTIR 2036750 · TMA1272105 | MSA TECHNOLOGY, LLC | 9 Electronics | Registered | 2024 |
| REBLOZYL 2029544 · TMA1118072 · design | Celgene Corporation | 5 Pharmaceuticals | Registered | 2022 |
| REFLEXION 2026477 · TMA1159927 | SEALY CANADA LTD./LTEE. | 20 Furniture | Registered | 2023 |