| REFPLUS 1574174 · TMA862090 | RefPlus Inc. | 11 Lighting | Registered | 2013 |
| REFPLUS 2269574 · design | RefPlus Inc. | 11 Lighting | Pending | 2023 |
| REPLIK 1177840 · TMA616121 | JCORP INC. | 18 Leather25 Clothing | Registered | 2004 |
| REPLAGAL 1346340 · TMA719639 · design | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals42 Science44 Medical | Registered | 2008 |
| REPLAGAL 1246415 · TMA652251 · design | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals | Registered | 2005 |
| REPLAGAL 1032514 · TMA633335 | SHIRE HUMAN GENETIC THERAPIES, INC. a Delaware corporation | 5 Pharmaceuticals | Registered | 2005 |
| REPLIGEN 0687084 · TMA404964 | REPLIGEN CORPORATION | 1 Chemicals5 Pharmaceuticals | Registered | 1992 |
| REPLICA 1944140 · TMA1204525 | MARGIELA | 3 Cosmetics | Registered | 2023 |
| REPLICA 1941111 · TMA1184495 | Replica Inc. | 42 Science | Registered | 2023 |
| REPLICA 1897879 · TMA1082814 · design | 9078-3184 QUÉBEC INC. | 9 Electronics42 Science | Registered | 2020 |
| REPLACE 1874744 · TMA1053112 | Edgewell Personal Care Brands, LLC | 8 Hand | Registered | 2019 |
| Revalús 1821398 · TMA1008880 | an individual | 9 Electronics16 Paper28 Toys+2 | Registered | 2018 |
| REPLICA 1751230 · TMA963032 | Integrated Beverage Group LLC | 33 Wine | Registered | 2017 |
| REPLIKA 1569025 · TMA858000 · design | 168406 CANADA INC. | 7 Machines8 Hand9 Electronics+2 | Registered | 2013 |
| REVOLUX 1442170 · TMA840545 | an individual | 6 Metal17 Rubber19 Building+2 | Registered | 2013 |
| REPLICO 1259564 · TMA675016 | REPLICO INC. | 19 Building39 Transport40 Treatment | Registered | 2006 |
| REOPLEX 0512212 · TMA294572 | Great Lakes Chemical Corporation | 1 Chemicals | Registered | 1984 |
| REPLACE 2316781 · design | REPLACE | 17 Rubber19 Building20 Furniture | Pending | 2023 |
| REPLAYZ 2288824 | Replayz Labs Ltd. | 9 Electronics16 Paper35 Advertising+1 | Pending | 2023 |
| REPLEXIUM 1881663 · TMA1076785 | Owner not shown | 1 Chemicals | Registered | 2020 |
| REPLIGRID 1407107 · TMA803860 | NEC CORPORATION | 9 Electronics | Registered | 2011 |
| RIPPLEX 2255970 · TMA1273166 | Ripple Labs Inc. | 41 Education | Registered | 2024 |
| Refilz 2255124 · TMA1276138 | 1000325553 ONTARIO LIMITED | 4 Oils | Registered | 2024 |
| Rivfloza 2182077 · TMA1212536 | Owner not shown | 5 Pharmaceuticals | Registered | 2023 |
| RIBOWELEC 2175886 · TMA1227086 | Shenzhen Ruibo Electronics Co. Ltd. | 9 Electronics | Registered | 2024 |