| SAFEPORT 2092977 · TMA1149451 | Targus International LLC | 9 Electronics | Registered | 2022 |
| SAFEFRAME 2088757 · TMA1184930 | TD IP Holdco, LLC | 6 Metal | Registered | 2023 |
| SAFEPRO 1889577 · TMA1084556 | Owner not shown | 1 Chemicals | Registered | 2020 |
| SAFEFRAME 1665728 · TMA1028904 | Little Giant Ladder Systems, LLC | 6 Metal20 Furniture | Registered | 2019 |
| SafePro 1449402 · TMA779016 | Fit-Rite Safety Wear Inc. | 9 Electronics25 Clothing35 Advertising | Registered | 2010 |
| Spebrick 2216310 · TMA1248284 | Shenzhen Love Earth Technology Co., Ltd. | 28 Toys | Registered | 2024 |
| SHIBEVER 2210289 · TMA1251046 · design | Guangzhou WoFei Trade Co.,Ltd | 25 Clothing | Registered | 2024 |
| SYFOVRE 2168758 · TMA1198198 | Apellis Pharmaceuticals, Inc. | 5 Pharmaceuticals | Registered | 2023 |
| SPEFRIU 2087122 · TMA1164904 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 5 Pharmaceuticals | Registered | 2023 |
| ShipOvers 2062940 · TMA1275563 | an individual | 39 Transport | Registered | 2024 |
| Shapeweaver 2040853 · TMA1147893 | an individual | 16 Paper | Registered | 2022 |
| SHOP4EVER 1885755 · TMA1086287 | Creative ACC, Inc. | 18 Leather21 Housewares25 Clothing+2 | Registered | 2020 |
| SPAVARO 1801633 · TMA1055424 | Spavaro Inc. | 3 Cosmetics35 Advertising40 Treatment+3 | Registered | 2019 |
| SIFIBER 1733974 · TMA1039750 | an individual | 7 Machines9 Electronics42 Science | Registered | 2019 |
| SAVAPEUR 1731041 · TMA956854 · design | an individual | 34 Tobacco | Registered | 2016 |
| SPEYBURN 1681147 · TMA910459 | INVER HOUSE DISTILLERS LIMITED | 33 Wine | Registered | 2015 |
| SafePartners 1644783 · TMA896835 | The CSL Group Inc. - Groupe CSL Inc. | 35 Advertising | Registered | 2015 |
| SPOVIRET 1633719 · TMA1035805 | an individual | 5 Pharmaceuticals | Registered | 2019 |
| SAFEPRODUCTION 1587238 · TMA907715 | Asplundh Investments, LLC | 45 Legal | Registered | 2015 |
| SAFEBRIDGE 1577115 · TMA860965 | Safebridge Holdings Ltd. | 36 Finance | Registered | 2013 |
| SKYPAVER 1509726 · TMA840199 | Holcim Solutions and Products US, LLC | 19 Building | Registered | 2013 |
| SKYFIBER 1442189 · TMA771140 | SkyFiber, Inc. | 9 Electronics16 Paper | Registered | 2010 |
| SPYBORGS 1390480 · TMA782791 | CAPCOM CO., LTD | 9 Electronics | Registered | 2010 |
| SPAPROTECT 1236395 · TMA655806 · design | IPG International Pool Group Inc. | 1 Chemicals | Registered | 2005 |
| SIPAPER 1225886 · TMA650628 | an individual | 9 Electronics37 Construction42 Science | Registered | 2005 |