| SASKWORKS 1256532 · TMA661561 · design | SaskWorks Venture Fund Inc. | 35 Advertising36 Finance | Registered | 2006 |
| SeisWorks 2283045 | ExGeo Corp. | 9 Electronics | Pending | 2023 |
| SAGRES 1816669 · TMA1064611 · design | Owner not shown | 29 Meat | Registered | 2019 |
| SAGRES 1615113 · TMA904476 · design | SCC-SOCIEDADE CENTRAL DE CERVEJAS E BEBIDAS, S.A. (a Portuguese company) | 32 Beer | Registered | 2015 |
| SAGARIS 1587694 · TMA925599 | A.T. Cross Company, LLC | 16 Paper | Registered | 2016 |
| SAGRES 0297610 · TMA148685 | SCC-SOCIEDADE CENTRAL DE CERVEJAS E BEBIDAS, S.A. (a Portuguese company) | 32 Beer | Registered | 1966 |
| SEAGERS 0213561 · UCA41477 | Independent Liquor (NZ) Limited | 33 Wine | Registered | 1952 |
| SUKERXIUS 2258919 · TMA1279275 · design | Henan Yaobo Home Technology Co., Ltd. | 11 Lighting | Registered | 2024 |
| SQUISHAROYS 2235760 · TMA1253092 | Kelly Toys Holdings, LLC | 28 Toys | Registered | 2024 |
| SECURESEAL 2225920 · TMA1251267 | The Procter & Gamble Company | 5 Pharmaceuticals | Registered | 2024 |
| SEEKERS 2200592 · TMA1282798 · design | DN3010 Limited | 9 Electronics35 Advertising41 Education | Registered | 2025 |
| SEEKERS 2190945 · TMA1282731 | DN3010 Limited | 9 Electronics35 Advertising41 Education | Registered | 2025 |
| SecureShop 2183257 · TMA1231292 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics36 Finance45 Legal | Registered | 2024 |
| SKECHERS 2179715 · TMA1250981 | Skechers U.S.A. Inc. II | 12 Vehicles27 Carpets | Registered | 2024 |
| SECURISEA 2141278 · TMA1207496 | SECURISEA, INC. | 9 Electronics42 Science | Registered | 2023 |
| SECURIIX 2135869 · TMA1197032 | 2325887 Ontario Inc. | 42 Science | Registered | 2023 |
| Soucrisp 2134249 · TMA1212033 | FutureStar Inc. | 9 Electronics | Registered | 2023 |
| SECUREGUARD 2130304 · TMA1210894 · design | Empowerment Technologies Inc. | 9 Electronics | Registered | 2023 |
| SecureContainer 2111540 · TMA1211881 | E-JAN NETWORKS Co. | 9 Electronics42 Science | Registered | 2023 |
| SECURECHOICE 2106598 · TMA1282430 · design | an individual | 9 Electronics37 Construction45 Legal | Registered | 2025 |
| SECURIGLOBE 2105474 · TMA1210718 · design | Sécuriglobe Inc. | 36 Finance | Registered | 2023 |
| SecureStretch 2097223 · TMA1278605 | Purple Innovation, LLC | 20 Furniture24 Textiles | Registered | 2024 |
| SECURESHUTTLE 2091106 · TMA1149383 | Cook Medical Technologies LLC | 42 Science | Registered | 2022 |
| SECUREASSIST 2070806 · TMA1282217 · design | Util-Assist Inc. | 45 Legal | Registered | 2025 |
| SECUREASSIST 2070800 · TMA1282216 | Util-Assist Inc. | 45 Legal | Registered | 2025 |