| SECOND 2 1149718 · TMA616588 · design | LES VÊTEMENTS WAZANA INC. | 25 Clothing | Registered | 2004 |
| 90 SECOND 2132913 · design | an individual | 41 Education | Pending | 2021 |
| SECOND ACT 2086116 · TMA1177473 | MARK ANTHONY GROUP INC. | 33 Wine | Registered | 2023 |
| SECOND ACT 1428753 · TMA817549 | BPI US Holding LLC, a limited Delaware liability company | 41 Education44 Medical45 Legal | Registered | 2012 |
| SECOND CUP 1402137 · TMA783751 · design | Foodtastic, Inc. | 6 Metal7 Machines9 Electronics+12 | Registered | 2010 |
| SECOND CUP 1288036 · TMA746947 · design | Foodtastic, Inc. | 9 Electronics11 Lighting16 Paper+8 | Registered | 2009 |
| SECOND CUP 1248257 · TMA667044 | Foodtastic, Inc. | 21 Housewares30 Coffee35 Advertising+2 | Registered | 2006 |
| SECOND CUT 2340856 | Owner not listed | 20 Furniture25 Clothing35 Advertising+2 | Pending | 2024 |
| SECOND UNIT 2231233 · TMA1253952 | an individual | 25 Clothing | Registered | 2024 |
| SECOND WIND 2145943 · TMA1202919 | Stockyards Beverage Company Inc. | 30 Coffee | Registered | 2023 |
| SECOND LOOK 1734822 · TMA1012506 | CAPITAL ONE FINANCIAL CORPORATION | 36 Finance45 Legal | Registered | 2019 |
| SECOND SKIN 1681242 · TMA926375 | American Sports Licensing, LLC | 25 Clothing | Registered | 2016 |
| SECOND STEP 1671461 · TMA982199 | an individual | 9 Electronics16 Paper41 Education+1 | Registered | 2017 |
| I AM SECOND 1428224 · TMA817918 | e3 Partners Ministry, Inc. | 9 Electronics16 Paper25 Clothing+3 | Registered | 2012 |
| SECOND LOOK 1312377 · TMA752905 | H&R Block Canada, Inc. | 35 Advertising | Registered | 2009 |
| SECOND STEP 1238720 · TMA664481 | an individual | 9 Electronics16 Paper28 Toys+1 | Registered | 2006 |
| SECOND BYTE 1139848 · TMA596736 | The Second Byte Inc. | 35 Advertising | Registered | 2003 |
| SECOND WIND 1020723 · TMA561901 | an individual | 10 Medical16 Paper28 Toys+1 | Registered | 2002 |
| SECOND WIND 0731343 · TMA473780 · design | an individual | 9 Electronics16 Paper34 Tobacco+1 | Registered | 1997 |
| SECOND CITY 0430367 · TMA246735 | The Second City, Inc. | 9 Electronics10 Medical14 Jewellery+8 | Registered | 1980 |
| SECOND & FOUR 2329466 · design | Owner not listed | 14 Jewellery18 Leather25 Clothing | Pending | 2024 |
| SECOND LIFE 2259054 | G2 REVOLUTION, LLC | 40 Treatment | Pending | 2023 |
| SECOND SHOT 2240538 | Yeti Coolers, LLC | 21 Housewares35 Advertising40 Treatment | Pending | 2023 |
| SECOND WAVE 2024511 | OCEAN SPRAY CRANBERRIES, INC. | 3 Cosmetics5 Pharmaceuticals29 Meat+2 | Pending | 2020 |
| SECOND WAVE 2016506 | CPI CG Inc. | 9 Electronics40 Treatment42 Science | Pending | 2020 |