| SESOTEC 1707363 · TMA957941 · design | Sesotec GmbH | 7 Machines9 Electronics | Registered | 2016 |
| Secotec 1668694 · TMA953114 | an individual | 7 Machines9 Electronics11 Lighting | Registered | 2016 |
| SESOTEC 1596433 · TMA888087 | Sesotec GmbH | 7 Machines9 Electronics | Registered | 2014 |
| SYSTECH 0644412 · TMA380890 | SYSTECH ENVIRONMENTAL CORPORATION | 42 Science | Registered | 1991 |
| SIGTECH 2283562 · design | Owner not listed | 9 Electronics36 Finance42 Science | Pending | 2023 |
| SIGTECH 2242638 | SIG Technologies Limited | 9 Electronics35 Advertising36 Finance+1 | Pending | 2022 |
| SWISSTECH 1933828 · TMA1146401 | Swisstech IP Co LLC | 12 Vehicles18 Leather21 Housewares+3 | Registered | 2022 |
| SWISSTECH 1738054 · TMA1028670 · design | Swisstech IP Co LLC | 25 Clothing | Registered | 2019 |
| SICKKIDS 2326427 · TMA1269211 | THE HOSPITAL FOR SICK CHILDREN | 9 Electronics16 Paper18 Leather+3 | Registered | 2024 |
| secetket 2266214 · TMA1253211 | Guangzhou infinite good luck e-commerce Co. LTD. | 25 Clothing | Registered | 2024 |
| SHASTACAD 2250377 · TMA1267448 | Shasta Industries, Inc | 9 Electronics42 Science | Registered | 2024 |
| SASQUATCH 2242240 · TMA1261696 | Sasquatch Heat Pumps Ltd. | 11 Lighting37 Construction42 Science | Registered | 2024 |
| SOSteacher 2197035 · TMA1198255 | SOSprof inc | 41 Education | Registered | 2023 |
| SIXTUS 2183780 · TMA1239656 | Sixtus GmbH | 3 Cosmetics5 Pharmaceuticals | Registered | 2024 |
| SISTICKER 2164675 · TMA1213333 | an individual | 28 Toys | Registered | 2023 |
| SHECODES 2161887 · TMA1212291 · design | an individual | 41 Education | Registered | 2023 |
| SISTACO 2065063 · TMA1133427 | Sistaco Pty Ltd | 3 Cosmetics | Registered | 2022 |
| SICOTAS 2058753 · TMA1154177 | Shenzhen Xingmailong Technology Co. Ltd. | 20 Furniture | Registered | 2022 |
| SIGHTSAVERS 2046733 · TMA1195219 · design | The Royal Commonwealth Society for the Blind | 9 Electronics35 Advertising36 Finance+1 | Registered | 2023 |
| SEKTAYOS 1991475 · TMA1260537 · design | Intercept Pharmaceuticals, Inc. | 5 Pharmaceuticals | Registered | 2024 |
| SEKTAYOS 1991473 · TMA1266306 | Intercept Pharmaceuticals, Inc. | 5 Pharmaceuticals | Registered | 2024 |
| SICKSTICK 1982021 · TMA1151229 · design | Vans, Inc. | 25 Clothing | Registered | 2022 |
| SICKSTICK 1982019 · TMA1151228 | Vans, Inc. | 25 Clothing | Registered | 2022 |
| SECTIGO 1929540 · TMA1139070 | Sectigo Limited | 9 Electronics35 Advertising38 Telecommunications+2 | Registered | 2022 |
| SIGHTSAGE 1916242 · TMA1115693 | SIGHTSAGE FOODS AND NUTRITION INC. | 5 Pharmaceuticals9 Electronics10 Medical+5 | Registered | 2021 |