| SWIFTRONICS 2356710 | Owner not listed | 35 Advertising | Pending | 2024 |
| SHOPATRON 1507931 · TMA815545 | Kibo Software, Inc. | 42 Science | Registered | 2012 |
| SHIPTRACK 1757320 · TMA958426 · design | ShipTrack Inc. | 9 Electronics35 Advertising42 Science | Registered | 2016 |
| SHIPTRACK 1757315 · TMA958427 | ShipTrack Inc. | 9 Electronics35 Advertising42 Science | Registered | 2016 |
| SOFTRON 0767625 · TMA447856 | SOFTRON COMPUTERS INC. | 35 Advertising | Registered | 1995 |
| SPEEDTRONIC 0511159 · TMA295543 | The Black & Decker Corporation (a Maryland corporation) | 7 Machines | Registered | 1984 |
| SHOPDROP 2096984 | SHOPDROP MARKETPLACE INC. | 9 Electronics35 Advertising42 Science+1 | Pending | 2021 |
| SOFTROC 2070162 | 2712128 Ontario Inc. | 19 Building35 Advertising37 Construction | Pending | 2020 |
| SPOTHERO 2309122 · TMA1283547 | SpotHero, Inc. | 9 Electronics39 Transport42 Science | Registered | 2025 |
| SPYDER 2265957 · TMA1285019 | SPYDER ACTIVE SPORTS, INC. | 18 Leather20 Furniture21 Housewares | Registered | 2025 |
| SPEEDREVO 2225316 · TMA1241907 | Mizuno Corporation | 25 Clothing | Registered | 2024 |
| Seovediary 2223198 · TMA1248809 | Qingdao Mingyuanbo Electronics Co., Ltd | 9 Electronics | Registered | 2024 |
| SPTRAMLE 2212448 · TMA1243115 · design | Shenzhen Xinchuang Garment Trading Co., Ltd. | 25 Clothing | Registered | 2024 |
| SAFEDROP 2199469 · TMA1223868 | Stericycle Inc. | 10 Medical40 Treatment | Registered | 2024 |
| SpiderMon 2183250 · TMA1230450 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics42 Science | Registered | 2024 |
| SUPATRAZ 2177651 · TMA1245099 · design | Vita (Europe) Limited | 5 Pharmaceuticals | Registered | 2024 |
| SOFTERFIX 2171762 · TMA1201983 | an individual | 17 Rubber20 Furniture | Registered | 2023 |
| Saboteur 2145081 · TMA1257689 | AMIGO Spiel + Freizeit GmbH | 28 Toys | Registered | 2024 |
| Speedrid 2133470 · TMA1213096 | LINEMART INC | 12 Vehicles | Registered | 2023 |
| SAIFTRAD 2110979 · TMA1197673 | Saiftrade Inc | 3 Cosmetics16 Paper | Registered | 2023 |
| SOFTDROPS 2107786 · TMA1179168 | The Ddrops Company Inc. | 5 Pharmaceuticals | Registered | 2023 |
| softrail 2098167 · TMA1239424 | an individual | 10 Medical | Registered | 2024 |
| SpiderTie 2088992 · TMA1202645 | Karl Storz SE & Co. KG | 10 Medical16 Paper | Registered | 2023 |
| SpiderBond 2088991 · TMA1180372 | Karl Storz SE & Co. KG | 10 Medical16 Paper | Registered | 2023 |
| SOFTRAID 2064933 · TMA1133419 | New Concepts Development Corporation | 9 Electronics | Registered | 2022 |