| SIDECAR 2284130 · TMA1108288 | Apple Inc. | 9 Electronics | Registered | 2021 |
| SIDECAR 1180432 · TMA674584 | Alfred Dunhill Limited | 9 Electronics14 Jewellery16 Paper+3 | Registered | 2006 |
| SEEDGUARD 2129671 | Seedex Inc. (a Delaware corporation) | 1 Chemicals31 Fresh | Pending | 2021 |
| SWITCHGUARD 1293166 · TMA711134 | Siemens Mobility GmbH | 7 Machines9 Electronics37 Construction+2 | Registered | 2008 |
| ScoutGuard 1459340 · TMA781663 | BOLY MEDIA COMMUNICATIONS (SHENZHEN) CO. LTD. | 7 Machines9 Electronics | Registered | 2010 |
| Sidegren 2154219 · TMA1228875 | an individual | 9 Electronics14 Jewellery18 Leather+2 | Registered | 2024 |
| SITESURE 1475145 · TMA847242 | Chubb Limited | 36 Finance | Registered | 2013 |
| SweatyShark 2263079 · TMA1281452 | an individual | 25 Clothing | Registered | 2025 |
| stickerfy 2232491 · TMA1254060 | an individual | 35 Advertising40 Treatment | Registered | 2024 |
| SUITESURGERY 2183721 · TMA1278882 · design | an individual | 10 Medical11 Lighting | Registered | 2024 |
| STCRC 2177910 · TMA1190049 | STCRC | 28 Toys | Registered | 2023 |
| SDGR 2152829 · TMA1198093 · design | HOSHINO GAKKI CO. LTD. | 15 Musical | Registered | 2023 |
| SEATCRAFT 2143577 · TMA1185529 | ORBO CORPORATION | 20 Furniture | Registered | 2023 |
| SHOTGRID 2128161 · TMA1222120 | Autodesk, Inc. | 42 Science | Registered | 2024 |
| STICKERAPP 2114913 · TMA1219066 · design | an individual | 6 Metal16 Paper20 Furniture+2 | Registered | 2024 |
| Sodagreen 2108819 · TMA1177757 | Yiwu Shousheng E-Commerce Co. Ltd. | 16 Paper | Registered | 2023 |
| SWEATSHEER 2100560 · TMA1173823 · design | KADENA INDUSTRIES LIMITED | 25 Clothing | Registered | 2023 |
| SETAGRIP 2099390 · TMA1216979 | OneFlor USA, LLC | 19 Building | Registered | 2024 |
| SUDOCREM 2082060 · TMA1149315 · design | Norton Creams Limited | 3 Cosmetics5 Pharmaceuticals | Registered | 2022 |
| SHOETIZER 2079005 · TMA1203852 | an individual | 11 Lighting | Registered | 2023 |
| SWEETGRASS 2076611 · TMA1154301 | Flower Love Canada Corp. | 8 Hand9 Electronics11 Lighting+3 | Registered | 2022 |
| STACKER 2064176 · TMA1193317 | METALTECH-OMEGA INC. | 6 Metal7 Machines8 Hand+6 | Registered | 2023 |
| STACKER 2064175 · TMA1193316 · design | METALTECH-OMEGA INC. | 6 Metal7 Machines8 Hand+6 | Registered | 2023 |
| STOCKYARDS 2062516 · TMA1239405 | IGNITE GROUP OF BRANDS INC. | 21 Housewares25 Clothing30 Coffee+5 | Registered | 2024 |
| SWITCHGEARMD 2062440 · TMA1278433 | ABB INC. | 9 Electronics | Registered | 2024 |