| SIMPLELOAD 1962162 · TMA1262047 · design | Miele & Cie, KG | 7 Machines | Registered | 2024 |
| SIMPLEAT 2249017 · TMA1266010 | Owner not listed | 29 Meat | Registered | 2024 |
| SimpleLAN 2183254 · TMA1231290 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLEAT 2168477 · TMA1245065 | Glanbia Nutritionals Limited | 1 Chemicals42 Science | Registered | 2024 |
| SIMPLELAB 2126437 · TMA1228799 | Simplelab, Inc. | 1 Chemicals42 Science | Registered | 2024 |
| SIMPLEWAY 2067779 · TMA1127575 · design | Xiaowei (Shanghai) Biotechnology Co.Ltd. | 21 Housewares | Registered | 2022 |
| SIMPLEWAY 2052037 · TMA1127527 · design | Xiaowei (Shanghai) Biotechnology Co.Ltd. | 3 Cosmetics | Registered | 2022 |
| SIMPLETAP 1596266 · TMA881738 | Belkin International, Inc. | 9 Electronics | Registered | 2014 |
| SimpleTax 1589860 · TMA859479 | SIMPLETAX SOFTWARE INC. | 9 Electronics35 Advertising | Registered | 2013 |
| SIMPLEXA 1470760 · TMA783699 | DIASORIN MOLECULAR LLC | 5 Pharmaceuticals9 Electronics10 Medical | Registered | 2010 |
| SIMPLEPAC 1463072 · TMA852562 | Owner not shown | 21 Housewares | Registered | 2013 |
| SIMPLEMAT 1439278 · TMA767911 | Custom Building Products, Inc. | 27 Carpets | Registered | 2010 |
| SIMPLERA 2131477 | an individual | 5 Pharmaceuticals | Pending | 2021 |
| SIMPLETREAD 1510918 · TMA817421 | Moulure Alexandria Moulding Inc. | 19 Building | Registered | 2012 |
| SimplEmail 2183251 · TMA1230451 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLEPASS 2181512 · TMA1230244 | The Gillette Company LLC | 8 Hand | Registered | 2024 |
| SIMPLESEAL 2010674 · TMA1145465 | Kenall Manufacturing Company | 11 Lighting | Registered | 2022 |
| SimpleGood 2001381 · TMA1137303 | an individual | 21 Housewares | Registered | 2022 |
| SIMPLESAVE 1398876 · TMA765796 · design | Hewlett-Packard Development Company, L.P. | 9 Electronics | Registered | 2010 |
| SIMPLESAVE 1395538 · TMA765175 | Hewlett-Packard Development Company, L.P. | 9 Electronics | Registered | 2010 |
| SIMPLETAPE 0810481 · TMA474437 | TRANS CONTINENTAL EQUIPMENT LTD. / ÉQUIPEMENT TRANS CONTINENTAL LTEE. | 1 Chemicals6 Metal20 Furniture+1 | Registered | 1997 |
| SIMPLESEAL 0810392 · TMA486253 | TRANS CONTINENTAL EQUIPMENT LTD. / ÉQUIPEMENT TRANS CONTINENTAL LTEE. | 1 Chemicals5 Pharmaceuticals6 Metal+4 | Registered | 1997 |
| SIMPLEBALE 2363658 | AGCO CORPORATION | 9 Electronics | Pending | 2024 |
| simplemark 2302750 | Hainan Sanlan Technology Holdings Co. Ltd. | 9 Electronics | Pending | 2023 |
| SimplexDNA 2180524 | an individual | 9 Electronics35 Advertising42 Science+1 | Pending | 2022 |