| SIMPLEBLOOM 2100163 · TMA1162663 | an individual | 31 Fresh | Registered | 2023 |
| SIMPLEFLOAT 2051152 | FloatSimple Inc. | 36 Finance | Pending | 2020 |
| SIMPLEHOOKS 2021446 | Luant Plastics Inc. | 6 Metal20 Furniture | Pending | 2020 |
| SYMPLELOANS 2061030 · TMA1211649 · design | Symple Loans Pty Limited | 9 Electronics36 Finance42 Science | Registered | 2023 |
| SIMPLESTAIRS 2021204 · TMA1179891 | MANNINGTON MILLS, INC. | 19 Building27 Carpets | Registered | 2023 |
| SimpleGood 2001381 · TMA1137303 | an individual | 21 Housewares | Registered | 2022 |
| SIMPLELOAD 1962162 · TMA1262047 · design | Miele & Cie, KG | 7 Machines | Registered | 2024 |
| SIMPLEFLEX 0810482 · TMA473923 | TRANS CONTINENTAL EQUIPMENT LTD. / ÉQUIPEMENT TRANS CONTINENTAL LTEE. | 6 Metal35 Advertising | Registered | 1997 |
| SIMPLECOOL 2348041 | Chengdu Hexin Pingyi Trading Co. Ltd. | 28 Toys | Pending | 2024 |
| SIMPLYCARS 2207577 · TMA1240360 · design | Grey Matter Data Inc. | 35 Advertising36 Finance | Registered | 2024 |
| SimpleLAN 2183254 · TMA1231290 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLEPASS 2181512 · TMA1230244 | The Gillette Company LLC | 8 Hand | Registered | 2024 |
| SIMPLELAB 2126437 · TMA1228799 | Simplelab, Inc. | 1 Chemicals42 Science | Registered | 2024 |
| simpletome 2062421 · TMA1173252 | SHENZHEN YOUPIN HOUSEWARE CO. LTD. | 21 Housewares | Registered | 2023 |
| SIMPLESTOP 2061053 · TMA1191515 | Future Motion, Inc. | 12 Vehicles | Registered | 2023 |
| SIMPLILOCK 1945862 · TMA1228598 | SimpliSafe, Inc. | 9 Electronics25 Clothing42 Science+1 | Registered | 2024 |
| SIMPLIFEYES 1910908 · TMA1100540 | SynergEyes, Inc. | 9 Electronics | Registered | 2021 |
| SIMPLICIOUS 1848589 · TMA1026814 | Brill, Inc. | 29 Meat30 Coffee | Registered | 2019 |
| SAMPLEPLUS 1792318 · TMA1050541 | Research Now Limited | 35 Advertising | Registered | 2019 |
| SIMPLECLICK 1766486 · TMA1046460 | Sun Pharmaceutical Industries Limited | 10 Medical | Registered | 2019 |
| SIMPLESTART 1685441 · TMA925914 | NCS MULTISTAGE, LLC | 6 Metal7 Machines37 Construction+1 | Registered | 2016 |
| SIMPLEBITES 1660155 · TMA909874 | Quinoa Corporation | 30 Coffee | Registered | 2015 |
| SIMPLYFLEX 1655566 · TMA895943 | Sealed Air Corporation (US) | 1 Chemicals | Registered | 2015 |
| SIMPLESLIDE 1604891 · TMA935317 | PBM Nutritionals, LLC | 5 Pharmaceuticals | Registered | 2016 |
| SIMPLECOTE 1566769 · TMA895217 | THE EMPIRE LIFE INSURANCE COMPANY | 9 Electronics | Registered | 2015 |