| SIMPLEMENTPROTÉGÉ 1905855 · TMA1130432 | The Canada Life Assurance Company | 36 Finance | Registered | 2022 |
| SIMPLYPREFERRED 1442745 · TMA800962 | Suncor Energy Inc. | 9 Electronics35 Advertising36 Finance | Registered | 2011 |
| Simpl. 2249458 · TMA1268687 | Owner not listed | 3 Cosmetics5 Pharmaceuticals35 Advertising | Registered | 2024 |
| SIMPLEAT 2249017 · TMA1266010 | Owner not listed | 29 Meat | Registered | 2024 |
| samfolk 2243070 · TMA1263019 | Owner not listed | 18 Leather | Registered | 2024 |
| Sunblue 2223600 · TMA1249985 | Sunblue Technology Ltd. | 9 Electronics | Registered | 2024 |
| simpleSwitch 2217775 · TMA1246724 | Simple Switch Canada Ltd. | 9 Electronics | Registered | 2024 |
| SIMPLYCARS 2207577 · TMA1240360 · design | Grey Matter Data Inc. | 35 Advertising36 Finance | Registered | 2024 |
| SIMPLYSOLID 2203587 · TMA1227356 | Givaudan SA | 1 Chemicals | Registered | 2024 |
| SIMPLYMENS 2201855 · TMA1272656 · design | an individual | 25 Clothing | Registered | 2024 |
| SIMPLE 2195373 · TMA1221645 | SIMPLE.LIFE APPS, INC. | 9 Electronics | Registered | 2024 |
| Skinfluence 2190143 · TMA1243979 | 2299463 ALBERTA LTD. | 35 Advertising | Registered | 2024 |
| Simpla 2188562 · TMA1232720 | Simpla Foods Inc. | 29 Meat30 Coffee | Registered | 2024 |
| SunplusTrade 2187459 · TMA1232567 | Hefei Zhunjia Trading Co. LTD | 6 Metal12 Vehicles | Registered | 2024 |
| SimpleLAN 2183254 · TMA1231290 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SimplEmail 2183251 · TMA1230451 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLEPASS 2181512 · TMA1230244 | The Gillette Company LLC | 8 Hand | Registered | 2024 |
| SONABLATE 2173315 · TMA1274101 | SONABLATE CORP. | 10 Medical | Registered | 2024 |
| SIMPLEAT 2168477 · TMA1245065 | Glanbia Nutritionals Limited | 1 Chemicals42 Science | Registered | 2024 |
| SENVELGO 2168468 · TMA1271082 · design | Boehringer Ingelheim Vetmedica GmbH | 5 Pharmaceuticals | Registered | 2024 |
| Simpletaste 2160230 · TMA1218483 | 1byone Products Inc. | 7 Machines21 Housewares | Registered | 2024 |
| someblokeyeg 2156836 · TMA1207844 | Owner not shown | 41 Education | Registered | 2023 |
| SIMPLIQ 2156438 · TMA1246295 · design | TOHATSU CORPORATION | 7 Machines9 Electronics | Registered | 2024 |
| SNAPFLO 2150404 · TMA1167257 | KOHLER CO. | 11 Lighting | Registered | 2023 |
| SUNNYFEEL 2150353 · TMA1206253 | Zhejiang Sunshine Leisure Products Co.Ltd. | 20 Furniture | Registered | 2023 |