| SIMPLEPROTECT 1905854 · TMA1130431 | The Canada Life Assurance Company | 36 Finance | Registered | 2022 |
| SIMPLEMENTPRÉFÉRENTIEL 1442746 · TMA800963 | Suncor Energy Inc. | 9 Electronics35 Advertising36 Finance | Registered | 2011 |
| SIMPLYPROTECT 1747338 · TMA1002885 | Edgewell Personal Care Brands, LLC | 3 Cosmetics | Registered | 2018 |
| SIMPLEMEASURE 1523813 · TMA894374 | Owner not shown | 5 Pharmaceuticals | Registered | 2015 |
| SIMPLECENTER 1309806 · TMA745904 | UNIVERSAL ELECTRONICS INC. | 9 Electronics | Registered | 2009 |
| SIMPLEPROBE 1180217 · TMA626180 · design | Roche Diagnostics GmbH | 1 Chemicals5 Pharmaceuticals | Registered | 2004 |
| SIMPLERETIRE 2231156 | TYREL CREATIVE INC. | 36 Finance41 Education42 Science | Pending | 2022 |
| SIMPLYPROTEIN 2121416 · design | Wellness Natural Inc. | 5 Pharmaceuticals29 Meat30 Coffee+2 | Pending | 2021 |
| Simpletaste 2160230 · TMA1218483 | 1byone Products Inc. | 7 Machines21 Housewares | Registered | 2024 |
| simpletome 2062421 · TMA1173252 | SHENZHEN YOUPIN HOUSEWARE CO. LTD. | 21 Housewares | Registered | 2023 |
| simpletaste 1878648 · TMA1067557 | 1byone Products Inc. | 11 Lighting21 Housewares | Registered | 2019 |
| SIMPLESTART 1685441 · TMA925914 | NCS MULTISTAGE, LLC | 6 Metal7 Machines37 Construction+1 | Registered | 2016 |
| SIMPLECOTE 1566769 · TMA895217 | THE EMPIRE LIFE INSURANCE COMPANY | 9 Electronics | Registered | 2015 |
| SIMPLEQUOTE 1566310 · TMA895080 | THE EMPIRE LIFE INSURANCE COMPANY | 9 Electronics | Registered | 2015 |
| SIMPLETREAD 1510918 · TMA817421 | Moulure Alexandria Moulding Inc. | 19 Building | Registered | 2012 |
| SimpleSondage 1362814 · TMA758179 | Les Solutions OutSideSoft Inc. | 9 Electronics35 Advertising42 Science | Registered | 2010 |
| Simpl. 2249458 · TMA1268687 | Owner not listed | 3 Cosmetics5 Pharmaceuticals35 Advertising | Registered | 2024 |
| SIMPLEAT 2249017 · TMA1266010 | Owner not listed | 29 Meat | Registered | 2024 |
| samfolk 2243070 · TMA1263019 | Owner not listed | 18 Leather | Registered | 2024 |
| Sunblue 2223600 · TMA1249985 | Sunblue Technology Ltd. | 9 Electronics | Registered | 2024 |
| simpleSwitch 2217775 · TMA1246724 | Simple Switch Canada Ltd. | 9 Electronics | Registered | 2024 |
| SIMPLYCARS 2207577 · TMA1240360 · design | Grey Matter Data Inc. | 35 Advertising36 Finance | Registered | 2024 |
| SIMPLYSOLID 2203587 · TMA1227356 | Givaudan SA | 1 Chemicals | Registered | 2024 |
| SIMPLYMENS 2201855 · TMA1272656 · design | an individual | 25 Clothing | Registered | 2024 |
| SIMPLE 2195373 · TMA1221645 | SIMPLE.LIFE APPS, INC. | 9 Electronics | Registered | 2024 |