| SIMPLEXA 1470760 · TMA783699 | DIASORIN MOLECULAR LLC | 5 Pharmaceuticals9 Electronics10 Medical | Registered | 2010 |
| SIMPLER 1259669 · TMA670872 | INTERNATIONAL BUSINESS MACHINES CORPORATION | 35 Advertising | Registered | 2006 |
| SimpleLAN 2183254 · TMA1231290 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLELAB 2126437 · TMA1228799 | Simplelab, Inc. | 1 Chemicals42 Science | Registered | 2024 |
| SIMPLEWAY 2067779 · TMA1127575 · design | Xiaowei (Shanghai) Biotechnology Co.Ltd. | 21 Housewares | Registered | 2022 |
| SIMPLEWAY 2052037 · TMA1127527 · design | Xiaowei (Shanghai) Biotechnology Co.Ltd. | 3 Cosmetics | Registered | 2022 |
| SIMPLETAP 1596266 · TMA881738 | Belkin International, Inc. | 9 Electronics | Registered | 2014 |
| SimpleTax 1589860 · TMA859479 | SIMPLETAX SOFTWARE INC. | 9 Electronics35 Advertising | Registered | 2013 |
| SIMPLEPAC 1463072 · TMA852562 | Owner not shown | 21 Housewares | Registered | 2013 |
| SIMPLEMAT 1439278 · TMA767911 | Custom Building Products, Inc. | 27 Carpets | Registered | 2010 |
| SIMPLERES 1402232 · TMA765501 | Marshall Anderson Tours Ltd. | 35 Advertising39 Transport41 Education+1 | Registered | 2010 |
| Simpledad 2374099 | Fuzhou Feibao Network Technology Co. Ltd. | 20 Furniture | Pending | 2025 |
| SIMPLEAT 2249017 · TMA1266010 | Owner not listed | 29 Meat | Registered | 2024 |
| SIMPLE 2195373 · TMA1221645 | SIMPLE.LIFE APPS, INC. | 9 Electronics | Registered | 2024 |
| Simpla 2188562 · TMA1232720 | Simpla Foods Inc. | 29 Meat30 Coffee | Registered | 2024 |
| SIMPLEAT 2168477 · TMA1245065 | Glanbia Nutritionals Limited | 1 Chemicals42 Science | Registered | 2024 |
| SIMPLEX 2116563 · TMA1222907 · design | an individual | 37 Construction | Registered | 2024 |
| SIMPLEX 2096048 · TMA1172664 | Simplex Services Inc. | 35 Advertising45 Legal | Registered | 2023 |
| SimpleTK 2045645 · TMA1150419 | Fitudio Inc. | 9 Electronics | Registered | 2022 |
| SIMPLE 1894715 · TMA1093561 · design | LOBLAWS INC. | 29 Meat30 Coffee32 Beer | Registered | 2021 |
| Simplex 1803404 · TMA1104125 | SKF Marine GmbH | 7 Machines12 Vehicles17 Rubber+3 | Registered | 2021 |
| SIMPLEX 1781532 · TMA1020924 | Leemark Spinnings Limited | 11 Lighting21 Housewares24 Textiles+1 | Registered | 2019 |
| SIMPLE 1769564 · TMA1025929 · design | DANONE INC. | 29 Meat | Registered | 2019 |
| SIMPLE 1708779 · TMA1045096 · design | The PNC Financial Services Group Inc. | 35 Advertising36 Finance42 Science | Registered | 2019 |
| SIMPLE 1708774 · TMA1045095 | The PNC Financial Services Group Inc. | 35 Advertising36 Finance42 Science | Registered | 2019 |