| SIMPLISTEEL 2294855 | Owner not listed | 6 Metal | Pending | 2023 |
| SEMPLIVEL 2139938 · TMA1239512 | Boehringer Ingelheim Vetmedica GmbH | 5 Pharmaceuticals | Registered | 2024 |
| Simplive 2075362 · TMA1162549 | an individual | 12 Vehicles | Registered | 2023 |
| SIMPLETEC 1621437 · TMA934346 | ROLF C. HAGEN INC. | 21 Housewares | Registered | 2016 |
| SIMPLICEF 1515786 · TMA870455 | Zoetis Services LLC | 5 Pharmaceuticals | Registered | 2014 |
| SIMPLICE 1325491 · TMA710725 | KOHLER CO. | 11 Lighting | Registered | 2008 |
| SIMPLATE 0815217 · TMA490494 | an individual | 5 Pharmaceuticals | Registered | 1998 |
| SIMPLICOL 0711868 · TMA434666 · design | BRAUNS-HEITMANN GMBH & CO. KG | 2 Paints | Registered | 1994 |
| SIMPLEBITES 1660155 · TMA909874 | Quinoa Corporation | 30 Coffee | Registered | 2015 |
| SIMPLICITEA 2329964 · design | Owner not listed | 32 Beer33 Wine | Pending | 2024 |
| SIMPLICITEA 2329960 | Owner not listed | 32 Beer33 Wine | Pending | 2024 |
| SIMPLESEAL 2010674 · TMA1145465 | Kenall Manufacturing Company | 11 Lighting | Registered | 2022 |
| SIMPLIFEYE 1956076 · TMA1224773 | Bausch + Lomb Ireland Limited | 5 Pharmaceuticals10 Medical | Registered | 2024 |
| SIMPLITUDE 1920474 · TMA1114909 | OWEN MUMFORD LIMITED | 9 Electronics10 Medical | Registered | 2021 |
| SIMPLICITÉ 1890915 · TMA1193076 | Canadian Tire Corporation, Limited | 3 Cosmetics8 Hand9 Electronics+8 | Registered | 2023 |
| SIMPLYLITE 1348390 · TMA723163 | Corelle Brands Holdings Inc. | 21 Housewares | Registered | 2008 |
| SIMPLIFLEX 1037650 · TMA557785 | The Canada Life Assurance Company | 36 Finance | Registered | 2002 |
| SIMPLESEAL 0810392 · TMA486253 | TRANS CONTINENTAL EQUIPMENT LTD. / ÉQUIPEMENT TRANS CONTINENTAL LTEE. | 1 Chemicals5 Pharmaceuticals6 Metal+4 | Registered | 1997 |
| SIMPLYTOLD 2263523 · design | OMNICOM INTERNATIONAL HOLDINGS, INC. | 35 Advertising | Pending | 2023 |
| SIMPLE 2195373 · TMA1221645 | SIMPLE.LIFE APPS, INC. | 9 Electronics | Registered | 2024 |
| SIMPLIQ 2156438 · TMA1246295 · design | TOHATSU CORPORATION | 7 Machines9 Electronics | Registered | 2024 |
| SIMPLINK 2140879 · TMA1209757 · design | Owner not shown | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| SIMPLEX 2116563 · TMA1222907 · design | an individual | 37 Construction | Registered | 2024 |
| SIMPLINK 2112357 · TMA1209643 | Owner not shown | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| SIMPLEX 2096048 · TMA1172664 | Simplex Services Inc. | 35 Advertising45 Legal | Registered | 2023 |