| SIMPLIQUE 1167535 · TMA633917 | an individual | 19 Building | Registered | 2005 |
| SIMPLISHADE 2074626 · TMA1138832 | Kerr Corporation | 5 Pharmaceuticals | Registered | 2022 |
| SIMPLITRACE 1709958 · TMA935498 | Attestra Inc. | 9 Electronics35 Advertising42 Science | Registered | 2016 |
| SIMPLISAFE 2104747 · TMA1219679 | SimpliSafe, Inc. | 9 Electronics11 Lighting42 Science | Registered | 2024 |
| Simplive 2075362 · TMA1162549 | an individual | 12 Vehicles | Registered | 2023 |
| simpletome 2062421 · TMA1173252 | SHENZHEN YOUPIN HOUSEWARE CO. LTD. | 21 Housewares | Registered | 2023 |
| SIMPLIFEYE 1956076 · TMA1224773 | Bausch + Lomb Ireland Limited | 5 Pharmaceuticals10 Medical | Registered | 2024 |
| SIMPLICITÉ 1890915 · TMA1193076 | Canadian Tire Corporation, Limited | 3 Cosmetics8 Hand9 Electronics+8 | Registered | 2023 |
| SIMPLISAFE 1876815 · TMA1089165 · design | SimpliSafe, Inc. | 9 Electronics42 Science45 Legal | Registered | 2020 |
| SIMPLIHOME 1815742 · TMA1016967 · design | CCT GLOBAL SOURCING INC. | 20 Furniture | Registered | 2019 |
| SIMPLIHOME 1815730 · TMA1016960 | CCT GLOBAL SOURCING INC. | 20 Furniture | Registered | 2019 |
| SIMPLISAFE 1723172 · TMA1034585 | SimpliSafe, Inc. | 9 Electronics42 Science | Registered | 2019 |
| SIMPLYTUFF 1655567 · TMA942364 | Sealed Air Corporation (US) | 1 Chemicals | Registered | 2016 |
| SimpliLine 1444781 · TMA803494 | Dallmer GmbH & Co. KG | 11 Lighting | Registered | 2011 |
| SIMPLICE 1325491 · TMA710725 | KOHLER CO. | 11 Lighting | Registered | 2008 |
| SIMPLIDOSE 1324043 · TMA708446 | an individual | 5 Pharmaceuticals10 Medical | Registered | 2008 |
| SIMPLITEL 0863791 · TMA517682 | an individual | 9 Electronics16 Paper38 Telecommunications | Registered | 1999 |
| SIMPLATE 0815217 · TMA490494 | an individual | 5 Pharmaceuticals | Registered | 1998 |
| SIMPLETAPE 0810481 · TMA474437 | TRANS CONTINENTAL EQUIPMENT LTD. / ÉQUIPEMENT TRANS CONTINENTAL LTEE. | 1 Chemicals6 Metal20 Furniture+1 | Registered | 1997 |
| SIMPLISAFE 2361834 · design | SimpliSafe, Inc. | 9 Electronics11 Lighting16 Paper+3 | Pending | 2024 |
| SIMPLICUT 2297928 | Kerr Corporation, U.S.A. Delaware Corporation | 10 Medical | Pending | 2023 |
| Simpletaste 2160230 · TMA1218483 | 1byone Products Inc. | 7 Machines21 Housewares | Registered | 2024 |
| SIMPLECURVE 2009322 · TMA1260692 | an individual | 6 Metal | Registered | 2024 |
| SIMPLISTOCK 1966501 · TMA1279698 · design | Retail Space Solutions LLC | 20 Furniture21 Housewares | Registered | 2024 |
| SIMPLISTICA 1945672 · TMA1084496 | Corn Products Development, Inc. | 1 Chemicals5 Pharmaceuticals | Registered | 2020 |