| SIMPLIVIA 1990690 | Simplivia Healthcare Ltd. | 5 Pharmaceuticals10 Medical44 Medical | Pending | 2019 |
| Simplive 2075362 · TMA1162549 | an individual | 12 Vehicles | Registered | 2023 |
| SIMPLICA 1356244 · TMA725948 · design | Vatti Corporation Limited | 7 Machines11 Lighting | Registered | 2008 |
| SIMPLIFYA 1949940 · TMA1182130 · design | Simplifya, LLC | 9 Electronics42 Science | Registered | 2023 |
| SIMPLIMAX 1772824 · TMA1054798 | i4 Solutions, Minnesota Limited Liability Company | 9 Electronics | Registered | 2019 |
| SIMPLICAM 1708329 · TMA1025447 | SimpliSafe, Inc. | 9 Electronics | Registered | 2019 |
| Simpla 2188562 · TMA1232720 | Simpla Foods Inc. | 29 Meat30 Coffee | Registered | 2024 |
| SIMPLIQ 2156438 · TMA1246295 · design | TOHATSU CORPORATION | 7 Machines9 Electronics | Registered | 2024 |
| SIMPLINK 2140879 · TMA1209757 · design | Owner not shown | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| SIMPLINK 2112357 · TMA1209643 | Owner not shown | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| SIMPLI5 2038822 · TMA1189155 | 5 Dynamics, LLC | 42 Science | Registered | 2023 |
| SIMPLIFI+ 2028256 · TMA1184706 | Pharmacy Onesource, Inc. | 42 Science | Registered | 2023 |
| SIMPLIST 2000630 · TMA1129020 · design | Simplist Technologies, Inc. | 9 Electronics35 Advertising42 Science | Registered | 2022 |
| Simplify 1880754 · TMA1105198 | Welspun India Limited | 20 Furniture24 Textiles27 Carpets | Registered | 2021 |
| SIMPLI 1859385 · TMA1027744 | Drylock Technologies N.V. naamloze vennootschap (abbreviation N.V.), a Belgian public limited company | 5 Pharmaceuticals | Registered | 2019 |
| SIMPLII 1852653 · TMA1056591 | CANADIAN IMPERIAL BANK OF COMMERCE | 35 Advertising36 Finance41 Education | Registered | 2019 |
| SIMPLIST 1792517 · TMA1033162 | FRESENIUS KABI USA, LLC | 5 Pharmaceuticals | Registered | 2019 |
| SIMPLIFY 1770506 · TMA967051 | U.S. Bank, N.A. | 9 Electronics | Registered | 2017 |
| SIMPLYA 1675825 · TMA904961 | Sealed Air Corporation (US) | 1 Chemicals | Registered | 2015 |
| SIMPLEXA 1470760 · TMA783699 | DIASORIN MOLECULAR LLC | 5 Pharmaceuticals9 Electronics10 Medical | Registered | 2010 |
| Simpli5 1400321 · TMA744980 | Ormco Corporation, (a Delaware Corporation) | 10 Medical | Registered | 2009 |
| SIMPLICE 1325491 · TMA710725 | KOHLER CO. | 11 Lighting | Registered | 2008 |
| SIMPLINK 1318161 · TMA751517 · design | LG ELECTRONICS INC. | 9 Electronics | Registered | 2009 |
| SIMPLERA 2131477 | an individual | 5 Pharmaceuticals | Pending | 2021 |
| Simpli 2044825 | Simpli Assets Ltd. | 10 Medical | Pending | 2020 |