| SONOBLASTER!! 1408637 · TMA768881 | Paedia LLC | 9 Electronics | Registered | 2010 |
| SYNFLATE 1556810 · TMA958010 | DePuy Synthes, Inc. | 10 Medical | Registered | 2016 |
| SUNBLAZE 0870617 · TMA514088 | The Conard-Pyle Company | 31 Fresh | Registered | 1999 |
| SUNBLASTER 2249416 | Owner not listed | 11 Lighting | Pending | 2023 |
| Sunblue 2223600 · TMA1249985 | Sunblue Technology Ltd. | 9 Electronics | Registered | 2024 |
| Sanabelle 2002068 · TMA1131060 | bosch Tiernahrung GmbH & Co. KG | 31 Fresh | Registered | 2022 |
| SNÖBLAD 1686339 · TMA1062482 · design | Snoblad Limited | 8 Hand9 Electronics18 Leather+3 | Registered | 2019 |
| SIMPLATE 0815217 · TMA490494 | an individual | 5 Pharmaceuticals | Registered | 1998 |
| SUNFLARE 2368914 | Summerland Varieties Corp. | 31 Fresh | Pending | 2024 |
| SNOWBLADE 2290981 | Amazon Technologies, Inc. | 9 Electronics38 Telecommunications42 Science | Pending | 2023 |
| SOMNOPLASTY 0857703 · TMA502006 | Gyrus ENT L.L.C. (a Delaware company) | 44 Medical | Registered | 1998 |
| Simpl. 2249458 · TMA1268687 | Owner not listed | 3 Cosmetics5 Pharmaceuticals35 Advertising | Registered | 2024 |
| SIMPLEAT 2249017 · TMA1266010 | Owner not listed | 29 Meat | Registered | 2024 |
| samfolk 2243070 · TMA1263019 | Owner not listed | 18 Leather | Registered | 2024 |
| simpleSwitch 2217775 · TMA1246724 | Simple Switch Canada Ltd. | 9 Electronics | Registered | 2024 |
| SIMPLYCARS 2207577 · TMA1240360 · design | Grey Matter Data Inc. | 35 Advertising36 Finance | Registered | 2024 |
| SIMPLYSOLID 2203587 · TMA1227356 | Givaudan SA | 1 Chemicals | Registered | 2024 |
| SIMPLYMENS 2201855 · TMA1272656 · design | an individual | 25 Clothing | Registered | 2024 |
| SIMPLE 2195373 · TMA1221645 | SIMPLE.LIFE APPS, INC. | 9 Electronics | Registered | 2024 |
| Skinfluence 2190143 · TMA1243979 | 2299463 ALBERTA LTD. | 35 Advertising | Registered | 2024 |
| Simpla 2188562 · TMA1232720 | Simpla Foods Inc. | 29 Meat30 Coffee | Registered | 2024 |
| SunplusTrade 2187459 · TMA1232567 | Hefei Zhunjia Trading Co. LTD | 6 Metal12 Vehicles | Registered | 2024 |
| SimpleLAN 2183254 · TMA1231290 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SimplEmail 2183251 · TMA1230451 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLEPASS 2181512 · TMA1230244 | The Gillette Company LLC | 8 Hand | Registered | 2024 |