| SPENCO 1457589 · TMA800832 | Implus Footcare, LLC | 25 Clothing | Registered | 2011 |
| SPENCO 0439950 · TMA280832 | Implus Footcare, LLC | 3 Cosmetics5 Pharmaceuticals7 Machines+13 | Registered | 1983 |
| SPINCO 2350837 · design | Owner not listed | 21 Housewares24 Textiles25 Clothing+2 | Pending | 2024 |
| SPINCO 2350832 · design | Owner not listed | 21 Housewares24 Textiles25 Clothing+2 | Pending | 2024 |
| SPINCO 2350831 · design | Owner not listed | 21 Housewares24 Textiles25 Clothing+2 | Pending | 2024 |
| SPINCO 1956858 | Spinco IP Holdings Inc. | 21 Housewares24 Textiles25 Clothing+2 | Pending | 2019 |
| SPONCOM 1740278 · TMA1001950 | Midwest Industrial Supply, Inc. a Ohio Corporation | 1 Chemicals | Registered | 2018 |
| Spank 1869359 · TMA1146258 | an individual | 3 Cosmetics5 Pharmaceuticals8 Hand+12 | Registered | 2022 |
| SPONCH 1671847 · TMA905668 | Owner not shown | 30 Coffee | Registered | 2015 |
| SPNC 1426156 · TMA809333 | THE SPECTRANETICS CORPORATION | 10 Medical | Registered | 2011 |
| SPENCE 1299174 · TMA711730 · design | Spence Diamonds Ltd. | 14 Jewellery35 Advertising | Registered | 2008 |
| !!SPONCH!! 1240795 · TMA742690 | Owner not shown | 30 Coffee | Registered | 2009 |
| SPANK 1129033 · TMA611670 | Ashbury Biologicals, Inc. a Corporation of Canada | 5 Pharmaceuticals | Registered | 2004 |
| SPANX 1092914 · TMA636581 | Spanx, LLC | 25 Clothing | Registered | 2005 |
| SPENCE 0876918 · TMA548730 · design | Spence Diamonds Ltd. | 14 Jewellery35 Advertising | Registered | 2001 |
| SPENCE 0317282 · TMA175268 · design | Emerson Process Management Regulator Technologies, Inc. | 6 Metal9 Electronics11 Lighting | Registered | 1971 |
| SPENCE 0317281 · TMA175267 | Emerson Process Management Regulator Technologies, Inc. | 9 Electronics11 Lighting | Registered | 1971 |
| SPANG 2305650 · design | Owner not listed | 21 Housewares | Pending | 2023 |
| SPINGO 0918140 · design | BRITISH COLUMBIA LOTTERY CORPORATION | 1 Chemicals2 Paints3 Cosmetics+42 | Pending | 2007 |
| SPINGO 0918138 | BRITISH COLUMBIA LOTTERY CORPORATION | 1 Chemicals2 Paints3 Cosmetics+42 | Pending | 2007 |
| SPENCORE 1472417 · TMA800833 | Implus Footcare, LLC | 17 Rubber | Registered | 2011 |
| SPINCORE 1438685 · TMA824566 | an individual | 9 Electronics10 Medical14 Jewellery+5 | Registered | 2012 |
| SOPHANCE 2266546 · design | Owner not listed | 1 Chemicals3 Cosmetics | Pending | 2023 |
| SPANESI 1927585 · TMA1171825 | an individual | 6 Metal7 Machines9 Electronics+2 | Registered | 2023 |
| SPINACH 1900997 · TMA1115270 · design | Cronos Group Inc. | 5 Pharmaceuticals9 Electronics14 Jewellery+7 | Registered | 2021 |