| SPANXSHAPE 2368223 | Spanx, LLC | 25 Clothing | Pending | 2024 |
| SPANSULE 0220099 · UCA45075 | GlaxoSmithKline Inc. | 5 Pharmaceuticals | Registered | 1953 |
| SPANSIVE 1976591 | Pi Inc. | 9 Electronics35 Advertising42 Science | Pending | 2019 |
| SPENSALL 1974591 · TMA1155913 | Fastenal IP Company | 6 Metal35 Advertising40 Treatment | Registered | 2022 |
| SPINACH 1900997 · TMA1115270 · design | Cronos Group Inc. | 5 Pharmaceuticals9 Electronics14 Jewellery+7 | Registered | 2021 |
| SPINACH 1893927 · TMA1115269 | Cronos Group Inc. | 5 Pharmaceuticals9 Electronics14 Jewellery+7 | Registered | 2021 |
| SPANKBANG 1889004 · TMA1084370 | MBB Ventures LLC | 38 Telecommunications41 Education42 Science | Registered | 2020 |
| SpinSeal 1832577 · TMA1014440 | Gestion Capital CDL inc. | 7 Machines17 Rubber | Registered | 2019 |
| SPANGLE 1654563 · TMA924019 | Universal Yarn, Inc. a North Carolina corporation | 23 Yarns | Registered | 2015 |
| SPINSENSE 1308120 · TMA732460 | LG ELECTRONICS INC. | 7 Machines11 Lighting | Registered | 2009 |
| SPENCE 1299174 · TMA711730 · design | Spence Diamonds Ltd. | 14 Jewellery35 Advertising | Registered | 2008 |
| SPINEASE 1293444 · TMA735207 | an individual | 18 Leather | Registered | 2009 |
| SPAMSMART 1184351 · TMA620111 | THE ELECTRIC MAIL COMPANY INC. | 38 Telecommunications | Registered | 2004 |
| SPANCO 1116296 · TMA602810 · design | SPANCO, INC. | 7 Machines12 Vehicles | Registered | 2004 |
| SPANCO 1061355 · TMA590259 | SPANCO, INC. | 7 Machines12 Vehicles | Registered | 2003 |
| SPENCE 0876918 · TMA548730 · design | Spence Diamonds Ltd. | 14 Jewellery35 Advertising | Registered | 2001 |
| SPINSTAR 0719129 · TMA434927 | GLOBERIDE, Inc. | 28 Toys | Registered | 1994 |
| SPANGLE 0632448 · TMA368270 | 3M Company (a Delaware corporation) | 3 Cosmetics | Registered | 1990 |
| SPUNCARE 0485537 · TMA282360 | O&M Halyard International Unlimited Company | 24 Textiles25 Clothing | Registered | 1983 |
| SPENCE 0317282 · TMA175268 · design | Emerson Process Management Regulator Technologies, Inc. | 6 Metal9 Electronics11 Lighting | Registered | 1971 |
| SPENCE 0317281 · TMA175267 | Emerson Process Management Regulator Technologies, Inc. | 9 Electronics11 Lighting | Registered | 1971 |
| SPANSET 0279879 · TMA139876 | an individual | 7 Machines10 Medical | Registered | 1965 |
| SPANCRETE 0256014 · TMA120802 | The Spancrete Group, Inc. | 19 Building | Registered | 1961 |
| "SPANSULES" 0215138 · UCA41347 | GlaxoSmithKline Inc. | 5 Pharmaceuticals | Registered | 1952 |
| Spunspon 2270797 | Shenzhen Youjiashun SupplyChainManagement Co.Ltd. | 21 Housewares | Pending | 2023 |