| SPREADSHIRT 1632083 · TMA906208 | Owner not shown | 18 Leather21 Housewares25 Clothing+1 | Registered | 2015 |
| SPREADSHOP 2243872 · TMA1183276 | Owner not shown | 35 Advertising38 Telecommunications40 Treatment+1 | Registered | 2023 |
| SPAREDENT 2157222 · TMA1252245 | Sparedent GmbH | 7 Machines10 Medical | Registered | 2024 |
| SPREADSHOP 2114279 · TMA1200086 | Owner not shown | 9 Electronics16 Paper18 Leather+5 | Registered | 2023 |
| SEAPORT 1689326 · TMA971361 | Lighthouse Brewing Company Inc. | 32 Beer | Registered | 2017 |
| SPREAD 1611166 · TMA1072480 | Spread Media, Inc. | 9 Electronics35 Advertising38 Telecommunications+2 | Registered | 2020 |
| SEAPORT 1575579 · TMA906882 | Brasstech, Inc. | 6 Metal11 Lighting20 Furniture+1 | Registered | 2015 |
| SPREAD 1559056 · TMA973904 | Spread Media, Inc. | 9 Electronics | Registered | 2017 |
| SPREADTRUM 1255415 · TMA730317 | SPREADTRUM COMMUNICATIONS INC. | 9 Electronics42 Science | Registered | 2008 |
| SPRAYIT 0326206 · TMA171141 | THOMAS INDUSTRIES, INC. | 2 Paints7 Machines9 Electronics | Registered | 1970 |
| SPREADSENSE 2369232 | Owner not listed | 9 Electronics | Pending | 2024 |
| SPREADTRUM 2265153 · design | Spreadtrum CommunicationsU.S.A. Inc. | 9 Electronics42 Science | Pending | 2023 |
| SPROUT 2326778 · TMA1267581 | THOR TECH, INC. | 12 Vehicles | Registered | 2024 |
| SPORTGEAR 2258981 · TMA1277830 · design | an individual | 25 Clothing | Registered | 2024 |
| speroto 2253896 · TMA1272989 | Hangzhou Yinan Technology Co. Ltd. | 14 Jewellery | Registered | 2024 |
| Shopperations 2245645 · TMA1264469 | Shopperations Research & Technology, LLC | 35 Advertising42 Science | Registered | 2024 |
| Sophproton 2240921 · TMA1262917 | Owner not listed | 25 Clothing | Registered | 2024 |
| SPEARTECH 2238306 · TMA1253132 | Owner not listed | 7 Machines9 Electronics12 Vehicles+1 | Registered | 2024 |
| SPEARTECH 2236779 · TMA1253097 · design | Owner not listed | 7 Machines9 Electronics12 Vehicles+1 | Registered | 2024 |
| SUPERTECK 2232357 · TMA1249016 | Superteck Experts-Conseils Inc. | 37 Construction41 Education | Registered | 2024 |
| SUPRADRY 2225244 · TMA1244495 · design | an individual | 11 Lighting | Registered | 2024 |
| SPROUT. 2217664 · TMA1245517 · design | Crown Worldwide Ltd. | 35 Advertising | Registered | 2024 |
| SPROUT 2217662 · TMA1245515 | Crown Worldwide Ltd. | 35 Advertising | Registered | 2024 |
| SPORTA 2212546 · TMA1244234 | an individual | 12 Vehicles | Registered | 2024 |
| Suphart 2207869 · TMA1254976 | an individual | 9 Electronics | Registered | 2024 |