| SPRIM 1998371 · TMA1129706 | SPRIM Americas, Inc. | 35 Advertising42 Science | Registered | 2022 |
| SPRIM 2282445 | StepStone Group Private Wealth, LLC | 36 Finance | Pending | 2023 |
| SOPROM 2274604 | Wuhan Zhade Science and Technology Ltd. | 21 Housewares | Pending | 2023 |
| SPIROMAX 2104898 · TMA1153294 | PATEK, PHILIPPE SA GENÈVE | 14 Jewellery | Registered | 2022 |
| SIPROMAC 1611282 · TMA884253 | Groupe Korok Inc. | 7 Machines11 Lighting | Registered | 2014 |
| SIPROMAC 1611278 · TMA884252 · design | Groupe Korok Inc. | 7 Machines11 Lighting | Registered | 2014 |
| SPERONI 1778621 · TMA991304 | an individual | 29 Meat | Registered | 2018 |
| SPERONI 1648013 · TMA920379 · design | an individual | 29 Meat | Registered | 2015 |
| SPARIUM 1442453 · TMA768912 | SOLARIUM RÉTRACTABLE SP INC. / RETRACTABLE SOLARIUM SP INC. | 6 Metal19 Building | Registered | 2010 |
| SPERIAN 1354241 · TMA767336 | an individual | 9 Electronics10 Medical22 Ropes+3 | Registered | 2010 |
| SUPRIMM 1246535 · TMA654289 | an individual | 5 Pharmaceuticals | Registered | 2005 |
| SPARMAX 1215863 · TMA640447 | Ding Hwa Co. Ltd. | 7 Machines | Registered | 2005 |
| SPERONE 2332652 | an individual | 33 Wine | Pending | 2024 |
| SUPERYAMA 1969574 · TMA1127831 | eYippee Group Limited | 9 Electronics12 Vehicles13 Firearms+3 | Registered | 2022 |
| SUPRIM 2239479 · TMA1259936 · design | MICRO-STAR INT'L CO. LTD. | 9 Electronics | Registered | 2024 |
| SUPERHUMAN 2228785 · TMA1267010 | Superhuman Inc. | 5 Pharmaceuticals30 Coffee32 Beer | Registered | 2024 |
| Springbank 2222034 · TMA1253788 | Springbank Mechanical Systems Limited | 37 Construction | Registered | 2024 |
| SUPERMOON 2215736 · TMA1233985 | Audiolineout LLC | 9 Electronics | Registered | 2024 |
| SOPRANO 2211840 · TMA1268462 | Alma Lasers Ltd. | 10 Medical | Registered | 2024 |
| SUPERNEUROS 2196870 · TMA1237315 · design | superneuros | 25 Clothing41 Education | Registered | 2024 |
| SUPERMOUTH 2196141 · TMA1238338 | Smile Makers LLC | 5 Pharmaceuticals9 Electronics10 Medical+7 | Registered | 2024 |
| SpringsYeaz 2194565 · TMA1235127 | Yiwu Chunye E-Commerce Co. Ltd. | 24 Textiles | Registered | 2024 |
| SPIREN 2190970 · TMA1234669 | an individual | 3 Cosmetics9 Electronics11 Lighting+2 | Registered | 2024 |
| SHOPFROMMARS 2190523 · TMA1237190 · design | an individual | 35 Advertising | Registered | 2024 |
| SprintScripts 2187033 · TMA1271145 | PLANET EARTH HEALTHCARE INC. | 35 Advertising39 Transport44 Medical | Registered | 2024 |