| SPYROS 1877251 · TMA1048998 | Bushnell Inc. | 13 Firearms | Registered | 2019 |
| SPYROS 1570958 · TMA867685 | KOHLER CO. | 11 Lighting | Registered | 2013 |
| SPORUS 2287638 | an individual | 3 Cosmetics25 Clothing | Pending | 2023 |
| SAPORUS 2049904 · TMA1275336 | Anchor Hocking, LLC | 21 Housewares | Registered | 2024 |
| SUPERUS 2244499 · design | Lingbao Machinery Equipment (Shenzhen) Co. Ltd | 9 Electronics | Pending | 2023 |
| SPURS 1869120 · TMA1091411 · design | TOTTENHAM HOTSPUR LIMITED | 6 Metal9 Electronics10 Medical+15 | Registered | 2021 |
| SPARKS 1454959 · TMA834500 | an individual | 9 Electronics16 Paper25 Clothing+2 | Registered | 2012 |
| SPIROS 1336707 · TMA769670 | ICU Medical, Inc. | 10 Medical | Registered | 2010 |
| SPARKS 1277922 · TMA713079 | GOLDEN VALLEY FOODS LTD. | 29 Meat35 Advertising40 Treatment | Registered | 2008 |
| SPIROS 1213484 · TMA680582 | Owner not shown | 30 Coffee43 Restaurants | Registered | 2007 |
| SPIROS 1019644 · TMA539671 · design | Owner not shown | 43 Restaurants | Registered | 2001 |
| SPARKS 0641033 · TMA407325 | Owner not shown | 8 Hand14 Jewellery16 Paper+3 | Registered | 1993 |
| SPARKS 0908485 | an individual | 1 Chemicals2 Paints3 Cosmetics+42 | Pending | 1998 |
| SPARQYS 2159830 · TMA1266827 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 5 Pharmaceuticals | Registered | 2024 |
| SPHEROS 1582424 · TMA900195 · design | Spheros GmbH | 6 Metal7 Machines9 Electronics+5 | Registered | 2015 |
| SPHEROS 1582420 · TMA900193 | Spheros GmbH | 6 Metal7 Machines9 Electronics+5 | Registered | 2015 |
| SAPHRIS 1486176 · TMA826999 | an individual | 5 Pharmaceuticals | Registered | 2012 |
| SEVERUS 1310327 · TMA692871 | AMSOIL, INC. | 40 Treatment42 Science | Registered | 2007 |
| SPHEROS 1054981 · TMA565271 | SHIMANO INC. a legal entity | 20 Furniture28 Toys | Registered | 2002 |
| SUPERUSER 1779711 · TMA1012531 | OpenStack Foundation, a non-stock, non profit corporation | 41 Education | Registered | 2019 |
| SUPERCUTS 0479776 · TMA320145 | SUPERCUTS INC. | 3 Cosmetics35 Advertising41 Education+1 | Registered | 1986 |
| SVIRG 2297090 · TMA1283527 | 9504-8807 Québec Inc. | 25 Clothing | Registered | 2025 |
| SUPERSPARK 2270850 · TMA1264600 | L'OREAL | 21 Housewares | Registered | 2024 |
| SHAPERX 2263475 · TMA1283257 | Shenzhen Yingxin Fashion Co. Ltd. | 25 Clothing | Registered | 2025 |
| SUPEREIGHT 2262254 · TMA1267518 | BJ Energy Solutions, LLC | 37 Construction | Registered | 2024 |