| SUBSITE 0856712 · TMA527964 | THE CHARLES MACHINE WORKS, INC. AN OKLAHOMA CORPORATION | 9 Electronics20 Furniture | Registered | 2000 |
| SUBSTIANE 1282039 · TMA680495 | an individual | 3 Cosmetics | Registered | 2007 |
| SUBKIT 2140013 · TMA1227926 | Subkit Inc. | 9 Electronics42 Science | Registered | 2024 |
| SUPSOD 1875450 · TMA1063133 · design | Shanghai Jianna Biological Technology Co. Ltd. | 29 Meat32 Beer | Registered | 2019 |
| SUBSTRATE 2014073 · TMA1160953 | Parity Technologies Limited | 9 Electronics35 Advertising41 Education+1 | Registered | 2023 |
| SUBSTANCE 1804196 · TMA1007321 | O'Neill Beverages Co. LLC | 33 Wine | Registered | 2018 |
| SJBOSTINE 2269702 | Owner not listed | 5 Pharmaceuticals18 Leather25 Clothing+1 | Pending | 2023 |
| SUBSTANCE 2266746 | O'Neill Beverages Co. LLC | 33 Wine | Pending | 2023 |
| SUBSTANTIVE 1363335 · TMA763331 | Owner not shown | 3 Cosmetics5 Pharmaceuticals | Registered | 2010 |
| SPOOKTACULAR 2292570 · TMA1267558 | PetSmart Home Office LLC | 31 Fresh | Registered | 2024 |
| SOPPYCID 2264505 · TMA1284863 · design | Dongguan Saienchuangke Technology Co. Ltd | 28 Toys | Registered | 2025 |
| SPECTRONORM 2256890 · TMA1277663 | VWR International Holdings, Inc. | 1 Chemicals | Registered | 2024 |
| SPXTEX 2248404 · TMA1271286 | an individual | 24 Textiles | Registered | 2024 |
| SPECTRALFX 2239740 · TMA1268513 | Owner not listed | 9 Electronics | Registered | 2024 |
| Shoephisticated 2229351 · TMA1259662 | Owner not shown | 20 Furniture | Registered | 2024 |
| SAVEST 2212104 · TMA1243066 | an individual | 36 Finance | Registered | 2024 |
| Supacat 2207901 · TMA1242777 | an individual | 20 Furniture | Registered | 2024 |
| suvectoro 2204900 · TMA1241307 | Suqian Xiangliang E-Commerce Co., Ltd. | 9 Electronics | Registered | 2024 |
| SpikeTides 2202014 · TMA1274226 | JPT Peptide Technologies GmbH | 1 Chemicals5 Pharmaceuticals | Registered | 2024 |
| SPECTIV 2180750 · TMA1265396 | DecisionWise, LLC | 42 Science | Registered | 2024 |
| SPECTRA 2180703 · TMA1212514 | LENCORE ACOUSTICS LLC | 9 Electronics | Registered | 2023 |
| SPECTRUM 2169090 · TMA1219923 | Spectrum Alberta Ltd. | 3 Cosmetics35 Advertising | Registered | 2024 |
| SPACTIVE 2168565 · TMA1245066 | CHT Germany GmbH | 1 Chemicals | Registered | 2024 |
| SpaceAid 2167331 · TMA1201908 | Bodwin Brothers LLC | 20 Furniture | Registered | 2023 |
| SPACITY 2164466 · TMA1220528 | KOHLER CO. | 11 Lighting20 Furniture21 Housewares | Registered | 2024 |