| ENCYCLOWEEDIA 1982411 | CANNCENTRAL INC. | 9 Electronics16 Paper35 Advertising+8 | Pending | 2019 |
| ENCYCLE 1773569 · TMA976228 | Encycle Therapeutics Inc. | 35 Advertising42 Science45 Legal | Registered | 2017 |
| encycle 1707320 · TMA984158 | Encycle Technologies, Inc. | 9 Electronics35 Advertising | Registered | 2017 |
| ENSACOVE 2300245 · TMA1103811 | Xcovery Holdings, Inc. | 5 Pharmaceuticals | Registered | 2021 |
| EMsights 2215794 · TMA1235230 | Artisan Partners Holdings LP | 36 Finance | Registered | 2024 |
| ENZOSUM 2212182 · TMA1243079 | Guangzhou Jingtu Leather Co., Ltd. | 18 Leather | Registered | 2024 |
| ENGAGE 2179851 · TMA1228386 | Medline Industries, LP | 25 Clothing | Registered | 2024 |
| Enyxus 2149828 · TMA1228869 | Enyxus, LLC | 42 Science | Registered | 2024 |
| ENJOYSTITCH 2134037 · TMA1187705 · design | Owner not shown | 9 Electronics | Registered | 2023 |
| Ensuqi 2116686 · TMA1183025 | an individual | 28 Toys | Registered | 2023 |
| ENJOUCA 2108708 · TMA1197671 · design | TETRA BIO-PHARMA INC. | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| ENKOSI 2101713 · TMA1234298 | Promotex Productions Inc | 27 Carpets | Registered | 2024 |
| Engage2Excel 2081226 · TMA1284134 | Engage2Excel Inc. | 35 Advertising41 Education42 Science | Registered | 2025 |
| ENJOX 2079323 · TMA1180210 | Shenzhen Aiyu Intelligent Technology Co. Ltd | 10 Medical | Registered | 2023 |
| Emoshayoga 2076397 · TMA1154300 | SHENZHEN CHUJIN NETWORK TECHNOLOGY CO.LTD | 20 Furniture | Registered | 2022 |
| ENJOUCA 2076262 · TMA1197590 | TETRA BIO-PHARMA INC. | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| ENSIGHTFUL 2050052 · TMA1273760 | Ensightful App Inc. | 9 Electronics42 Science | Registered | 2024 |
| ENGEOACTIONS 2021335 · TMA1132256 | Association of Professional Engineers and Geoscientists of New Brunswick | 9 Electronics | Registered | 2022 |
| ENSIGNIUM 2011051 · TMA1167621 | ENGINEERED FLOORS, LLC | 19 Building27 Carpets | Registered | 2023 |
| ENZOIC 1983644 · TMA1096842 | PasswordPing Ltd. | 42 Science | Registered | 2021 |
| ENGAGE 1975602 · TMA1240543 | Prentke Romich Company | 9 Electronics | Registered | 2024 |
| ENGAGE 1962555 · TMA1230859 | MAGNUM MAGNETICS CORPORATION | 9 Electronics | Registered | 2024 |
| ENGAGE 1958944 · TMA1119989 | PENN FISHING TACKLE MFG. CO. | 28 Toys | Registered | 2022 |
| ENOSYS 1954426 · TMA1096557 · design | Enosys Technology Corporation | 9 Electronics | Registered | 2021 |
| ENGAGE 1931371 · TMA1143208 | NATIONAL TOUR ASSOCIATION, INC. a legal entity | 38 Telecommunications42 Science | Registered | 2022 |