| ISOZONE 1452722 · TMA834459 | STRYKER CORPORATION | 10 Medical20 Furniture | Registered | 2012 |
| ISOCONE 1385679 · TMA790602 | ACROLAB LTD. | 6 Metal | Registered | 2011 |
| IXHIGMA 2226829 · TMA1244501 | GLAXO GROUP LIMITED | 5 Pharmaceuticals | Registered | 2024 |
| IUYKICN 2204307 · TMA1240072 | Shenzhen Yuanyangming Trading Co., Ltd. | 3 Cosmetics | Registered | 2024 |
| ICEGAN 2106774 · TMA1163709 | Cambridge GaN Devices Limited | 9 Electronics | Registered | 2023 |
| ICOSCAN 2099777 · TMA1227744 | ICONEUS | 9 Electronics | Registered | 2024 |
| ICAGEN 2074596 · TMA1138830 · design | Icagen, LLC | 42 Science | Registered | 2022 |
| ISOCONVERSION 1928565 · TMA1109293 | Chevron Intellectual Property LLC | 1 Chemicals | Registered | 2021 |
| iChicken 1858732 · TMA1018898 | an individual | 5 Pharmaceuticals7 Machines16 Paper+5 | Registered | 2019 |
| ICEKNOTS 1854395 · TMA1053185 · design | Zed Connections Inc. | 28 Toys | Registered | 2019 |
| iscosMec 1842490 · TMA1055275 | TRIDL INC. | 3 Cosmetics35 Advertising39 Transport | Registered | 2019 |
| IQOSCIENCE 1807579 · TMA1045044 | an individual | 35 Advertising42 Science | Registered | 2019 |
| IceContact 1773866 · TMA970687 | CONTINENTAL REIFEN DEUTSCHLAND GMBH | 12 Vehicles | Registered | 2017 |
| ICEGEN 1761066 · TMA959251 · design | IceGen Patent Corp. | 6 Metal11 Lighting19 Building+1 | Registered | 2017 |
| ISOCHEM 1683737 · TMA932552 | Pulsafeeder, Inc. | 7 Machines9 Electronics | Registered | 2016 |
| ICESUN 1675502 · TMA925832 | Icesun Vacuum Glass Ltd. | 7 Machines11 Lighting19 Building+2 | Registered | 2016 |
| IGUZZINI 1632443 · TMA910272 · design | an individual | 9 Electronics11 Lighting | Registered | 2015 |
| ISAACMIZRAHILIVE 1627004 · TMA939610 | IM TOPCO, LLC | 9 Electronics14 Jewellery18 Leather+1 | Registered | 2016 |
| ICESHINE 1593177 · TMA849128 | an individual | 12 Vehicles | Registered | 2013 |
| iSigner 1557849 · TMA960110 | iCommunicator LLC (a Delaware limited liability company) | 38 Telecommunications | Registered | 2017 |
| ISACOMFORT 1485330 · TMA890873 | ISAGENIX WORLDWIDE, INC. | 5 Pharmaceuticals | Registered | 2014 |
| IceCenter 1408277 · TMA802169 | an individual | 11 Lighting | Registered | 2011 |
| ICHIKAMI 1405123 · TMA786709 · design | Kracie, Ltd. | 3 Cosmetics5 Pharmaceuticals | Registered | 2011 |
| iSeismograph 1367055 · TMA781619 | Engineering Seismology Group Canada Inc. | 9 Electronics | Registered | 2010 |
| ISOKINE 1350129 · TMA831984 | Owner not shown | 1 Chemicals3 Cosmetics5 Pharmaceuticals+6 | Registered | 2012 |