| OPTIVANTAGE 2151402 · TMA1188820 | Liebel-Flarsheim Company LLC | 10 Medical | Registered | 2023 |
| Optave 2252460 · TMA1271440 | an individual | 9 Electronics35 Advertising41 Education+1 | Registered | 2024 |
| OPTABLATE 2126765 · TMA1173951 | STRYKER CORPORATION | 10 Medical | Registered | 2023 |
| OPTAVIA 1783974 · TMA1031913 · design | JASON ENTERPRISES, INC. | 5 Pharmaceuticals21 Housewares28 Toys+5 | Registered | 2019 |
| OPTAVIA 1755527 · TMA1056329 | JASON ENTERPRISES, INC. | 5 Pharmaceuticals21 Housewares28 Toys+5 | Registered | 2019 |
| OPTIVENT 1626002 · TMA933417 | Sivantos Pte. Ltd. | 10 Medical | Registered | 2016 |
| OPTIVENT 0369381 · TMA204385 | an individual | 7 Machines11 Lighting | Registered | 1975 |
| OPTIVENT 2018596 | Baby Jogger, LLC | 12 Vehicles20 Furniture24 Textiles | Pending | 2020 |
| OPTIVENT 1974233 | InterGuss Gießereiprodukte GmbH and MFSA Modell- und Formenbau GmbH Sachen-Anhalt | 7 Machines37 Construction42 Science | Pending | 2019 |
| OPTOPLUS 2249369 · TMA1237808 | Owner not listed | 5 Pharmaceuticals9 Electronics35 Advertising+2 | Registered | 2024 |
| OPTIPEER 2249080 · TMA1266020 | Owner not listed | 42 Science | Registered | 2024 |
| OPTHOPATCH 2189840 · TMA1233641 | Defined Vision Corp | 5 Pharmaceuticals | Registered | 2024 |
| OPTIBLUE 2189665 · TMA1246394 | Johnson & Johnson Surgical Vision, Inc. | 9 Electronics | Registered | 2024 |
| Optiva 2182917 · TMA1230374 | Shenzhen Verdewell Technology Limited | 34 Tobacco | Registered | 2024 |
| OPTIFLOW 2170393 · TMA1201970 | Fisher & Paykel Healthcare Limited | 44 Medical | Registered | 2023 |
| OPHTHAVET 2168013 · TMA1219903 | Dechra Veterinary Products, LLC | 5 Pharmaceuticals | Registered | 2024 |
| OPTIVIS 2158632 · TMA1196014 | Aaren Scientific Inc. | 10 Medical | Registered | 2023 |
| OPTIVIO 2140082 · TMA1180856 | Optivio, Inc. | 9 Electronics35 Advertising42 Science | Registered | 2023 |
| OptiPrep 2139843 · TMA1246208 | an individual | 1 Chemicals5 Pharmaceuticals | Registered | 2024 |
| OPTIBLEND 2119649 · TMA1207429 | Ritchie-Smith Feeds, Inc. | 5 Pharmaceuticals31 Fresh40 Treatment | Registered | 2023 |
| OPTIPRIME 2105308 · TMA1201335 | Pixelle Specialty Solutions LLC | 16 Paper | Registered | 2023 |
| OPTIBOOST 2103134 · TMA1225002 | an individual | 7 Machines11 Lighting31 Fresh+1 | Registered | 2024 |
| OPTIBERRY 2089967 · TMA1186081 | an individual | 5 Pharmaceuticals | Registered | 2023 |
| OPTIPLUS 2074646 · TMA1224947 | The Hilsinger Company Parent, LLC | 3 Cosmetics21 Housewares | Registered | 2024 |
| OPTYBI 2044141 · TMA1123220 | an individual | 5 Pharmaceuticals | Registered | 2022 |