| SIMPLEBITES 1660155 · TMA909874 | Quinoa Corporation | 30 Coffee | Registered | 2015 |
| SIMPLYMENS 2201855 · TMA1272656 · design | an individual | 25 Clothing | Registered | 2024 |
| SimpleLAN 2183254 · TMA1231290 | 1429481 Ontario Inc.(does business as Pathway Communications) | 9 Electronics38 Telecommunications42 Science | Registered | 2024 |
| SIMPLEPASS 2181512 · TMA1230244 | The Gillette Company LLC | 8 Hand | Registered | 2024 |
| SIMPLINK 2140879 · TMA1209757 · design | SOCIETE DES PRODUITS NESTLE S.A. | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| SIMPLINK 2112357 · TMA1209643 | SOCIETE DES PRODUITS NESTLE S.A. | 5 Pharmaceuticals10 Medical | Registered | 2023 |
| SIMPLEWAY 2067779 · TMA1127575 · design | Xiaowei (Shanghai) Biotechnology Co.Ltd. | 21 Housewares | Registered | 2022 |
| SIMPLEWAY 2052037 · TMA1127527 · design | Xiaowei (Shanghai) Biotechnology Co.Ltd. | 3 Cosmetics | Registered | 2022 |
| SIMPLESYNC 2002797 · TMA1258873 | BOSE CORPORATION | 9 Electronics | Registered | 2024 |
| SimpliLine 1444781 · TMA803494 | Dallmer GmbH & Co. KG | 11 Lighting | Registered | 2011 |
| SIMPLERES 1402232 · TMA765501 | Marshall Anderson Tours Ltd. | 35 Advertising39 Transport41 Education+1 | Registered | 2010 |
| SIMPLINK 1318161 · TMA751517 · design | LG ELECTRONICS INC. | 9 Electronics | Registered | 2009 |
| SIMPLEFIT 2307414 | LF, LLC | 11 Lighting | Pending | 2024 |
| SimplexDNA 2180524 | an individual | 9 Electronics35 Advertising42 Science+1 | Pending | 2022 |
| SIMPLELIFE 2014011 | Viaction Assurance inc. | 36 Finance | Pending | 2020 |
| simpleSwitch 2217775 · TMA1246724 | Simple Switch Canada Ltd. | 9 Electronics | Registered | 2024 |
| SIMPLESTAIRS 2021204 · TMA1179891 | MANNINGTON MILLS, INC. | 19 Building27 Carpets | Registered | 2023 |
| SYMPLELOANS 2061030 · TMA1211649 · design | Symple Loans Pty Limited | 9 Electronics36 Finance42 Science | Registered | 2023 |
| SIMPLICIOUS 1848589 · TMA1026814 | Brill, Inc. | 29 Meat30 Coffee | Registered | 2019 |
| SIMPLISTICS 1834544 · TMA1054268 | ArcBest IP Holdings, LLC | 35 Advertising37 Construction39 Transport | Registered | 2019 |
| SIMPLECLICK 1766486 · TMA1046460 | Sun Pharmaceutical Industries Limited | 10 Medical | Registered | 2019 |
| SIMPLESLIDE 1604891 · TMA935317 | PBM Nutritionals, LLC | 5 Pharmaceuticals | Registered | 2016 |
| SIMPLISTICS 2243312 | Owner not listed | 9 Electronics35 Advertising42 Science | Pending | 2023 |
| SIMPLEHOOKS 2021446 | Luant Plastics Inc. | 6 Metal20 Furniture | Pending | 2020 |
| SIMPLEPARGNES 1420262 · TMA771164 | THE TORONTO-DOMINION BANK | 36 Finance | Registered | 2010 |