| SIMPLICIM 1431547 · TMA766075 | Clinique Mireille Faucher inc. | 44 Medical | Registered | 2010 |
| SIMPLICA 1356244 · TMA725948 · design | Vatti Corporation Limited | 7 Machines11 Lighting | Registered | 2008 |
| SIMPLIMAX 1772824 · TMA1054798 | i4 Solutions, Minnesota Limited Liability Company | 9 Electronics | Registered | 2019 |
| SIMPLICON 1693599 · TMA981650 | an individual | 1 Chemicals | Registered | 2017 |
| SIMPLICEF 1515786 · TMA870455 | Zoetis Services LLC | 5 Pharmaceuticals | Registered | 2014 |
| SIMPLICE 1325491 · TMA710725 | KOHLER CO. | 11 Lighting | Registered | 2008 |
| SIMPLICOL 0711868 · TMA434666 · design | BRAUNS-HEITMANN GMBH & CO. KG | 2 Paints | Registered | 1994 |
| Simplecom 2326306 | SIMPLECOM AUSTRALIA PTY LTD | 9 Electronics11 Lighting | Pending | 2024 |
| SIMPLICUT 2297928 | Kerr Corporation, U.S.A. Delaware Corporation | 10 Medical | Pending | 2023 |
| simpliva 2251003 | Faisha Online Retail Limited | 20 Furniture | Pending | 2023 |
| SIMPLYCARS 2207577 · TMA1240360 · design | Grey Matter Data Inc. | 35 Advertising36 Finance | Registered | 2024 |
| SIMPLISAFE 2104747 · TMA1219679 | SimpliSafe, Inc. | 9 Electronics11 Lighting42 Science | Registered | 2024 |
| SIMPLICITY 2049958 · TMA1240846 | Barrette Outdoor Living, Inc | 6 Metal | Registered | 2024 |
| SIMPLICITY 2011518 · TMA1259108 | an individual | 44 Medical | Registered | 2024 |
| SIMPLICITY 1936530 · TMA1152516 | PerkinElmer U.S. LLC | 9 Electronics | Registered | 2022 |
| SIMPLICITY 1898543 · TMA1126598 | SWIMC LLC | 2 Paints | Registered | 2022 |
| SIMPLICITÉ 1890915 · TMA1193076 | Canadian Tire Corporation, Limited | 3 Cosmetics8 Hand9 Electronics+8 | Registered | 2023 |
| SIMPLISAFE 1876815 · TMA1089165 · design | SimpliSafe, Inc. | 9 Electronics42 Science45 Legal | Registered | 2020 |
| SIMPLICITI 1842496 · TMA1013738 | Howmedica Osteonics Corp. | 10 Medical | Registered | 2019 |
| SIMPLICiTY 1826084 · TMA1087799 | Videojet Technologies Inc. | 7 Machines9 Electronics16 Paper | Registered | 2020 |
| SIMPLIHOME 1815742 · TMA1016967 · design | CCT GLOBAL SOURCING INC. | 20 Furniture | Registered | 2019 |
| SIMPLIHOME 1815730 · TMA1016960 | CCT GLOBAL SOURCING INC. | 20 Furniture | Registered | 2019 |
| SIMPLICITY 1809059 · TMA1014540 · design | WESTJET AIRLINES LTD. | 35 Advertising39 Transport | Registered | 2019 |
| SIMPLICITY 1809057 · TMA1014544 | WESTJET AIRLINES LTD. | 35 Advertising39 Transport | Registered | 2019 |
| SIMPLISAFE 1723172 · TMA1034585 | SimpliSafe, Inc. | 9 Electronics42 Science | Registered | 2019 |