| SIMPLITUDE 1920474 · TMA1114909 | OWEN MUMFORD LIMITED | 9 Electronics10 Medical | Registered | 2021 |
| SIMPLYTOLD 2263523 · design | OMNICOM INTERNATIONAL HOLDINGS, INC. | 35 Advertising | Pending | 2023 |
| SimplyU 2072062 | an individual | 25 Clothing | Pending | 2020 |
| SIMPLYTHICK 1380043 · TMA742320 | Simply Thick, LLC | 5 Pharmaceuticals30 Coffee | Registered | 2009 |
| SIMPLYQUALIFY 2049723 · TMA1273750 | Bread Financial Payments, Inc. | 36 Finance | Registered | 2024 |
| SIMPLYCARS 2207577 · TMA1240360 · design | Grey Matter Data Inc. | 35 Advertising36 Finance | Registered | 2024 |
| SIMPLYMENS 2201855 · TMA1272656 · design | an individual | 25 Clothing | Registered | 2024 |
| SIMPLYMDRN 2129716 · TMA1192076 | simplyecom inc. | 9 Electronics18 Leather21 Housewares | Registered | 2023 |
| SIMPLISAFE 2104747 · TMA1219679 | SimpliSafe, Inc. | 9 Electronics11 Lighting42 Science | Registered | 2024 |
| simpletome 2062421 · TMA1173252 | SHENZHEN YOUPIN HOUSEWARE CO. LTD. | 21 Housewares | Registered | 2023 |
| SimpleTK 2045645 · TMA1150419 | Fitudio Inc. | 9 Electronics | Registered | 2022 |
| SIMPLIFI+ 2028256 · TMA1184706 | Pharmacy Onesource, Inc. | 42 Science | Registered | 2023 |
| SIMPLYJNJ 1967011 · TMA1138994 | an individual | 10 Medical25 Clothing | Registered | 2022 |
| SIMPLY 1931811 · TMA1190191 · design | Frito-Lay North America, Inc. | 29 Meat30 Coffee | Registered | 2023 |
| SIMPLYPHP 1926622 · TMA1113547 | SimplyPHP Inc. | 42 Science | Registered | 2021 |
| Simplify 1880754 · TMA1105198 | Welspun India Limited | 20 Furniture24 Textiles27 Carpets | Registered | 2021 |
| Simply 1879346 · TMA1104013 | Simply Gum Inc | 30 Coffee | Registered | 2021 |
| SIMPLISAFE 1876815 · TMA1089165 · design | SimpliSafe, Inc. | 9 Electronics42 Science45 Legal | Registered | 2020 |
| SIMPLOT 1862550 · TMA1021155 · design | J.R. SIMPLOT COMPANY | 1 Chemicals29 Meat30 Coffee | Registered | 2019 |
| SIMPLOT 1862545 · TMA1021154 · design | J.R. SIMPLOT COMPANY | 1 Chemicals29 Meat30 Coffee | Registered | 2019 |
| SIMPLYGON 1820672 · TMA1070337 | Microsoft Corporation | 9 Electronics42 Science | Registered | 2020 |
| SIMPLOT 1787415 · TMA995071 | J.R. SIMPLOT COMPANY | 1 Chemicals29 Meat30 Coffee | Registered | 2018 |
| SIMPLIFY 1770506 · TMA967051 | U.S. Bank, N.A. | 9 Electronics | Registered | 2017 |
| SIMPLISAFE 1723172 · TMA1034585 | SimpliSafe, Inc. | 9 Electronics42 Science | Registered | 2019 |
| SIMPLY 9 1716554 · TMA1017334 | SOCIETE DES PRODUITS NESTLE S.A. | 31 Fresh | Registered | 2019 |