| SANPAOLO 0738845 · TMA454578 · design | an individual | 35 Advertising36 Finance42 Science | Registered | 1996 |
| SIMPALO 1997998 · TMA1156942 | KOHLER CO. | 11 Lighting | Registered | 2022 |
| SYNPOL 1845380 · TMA1014156 · design | SPECIALIZED DESANDERS INC. | 5 Pharmaceuticals7 Machines9 Electronics+10 | Registered | 2019 |
| SYNPOL 1821229 · TMA1014142 | SPECIALIZED DESANDERS INC. | 5 Pharmaceuticals7 Machines9 Electronics+10 | Registered | 2019 |
| SUNPOLY 1484118 · TMA866968 | Sun Chemical Corporation | 2 Paints | Registered | 2013 |
| SKINFOLIO 1928431 · TMA1140737 | Skinfolio Medical Inc. | 3 Cosmetics4 Oils5 Pharmaceuticals+6 | Registered | 2022 |
| SHINEFLO 1773459 · TMA968362 · design | Fujian Aidi Electric Co. Ltd. | 7 Machines | Registered | 2017 |
| SINNVOLL 2215489 · design | an individual | 35 Advertising36 Finance41 Education | Pending | 2022 |
| Simpl. 2249458 · TMA1268687 | Owner not listed | 3 Cosmetics5 Pharmaceuticals35 Advertising | Registered | 2024 |
| SIMPLE 2195373 · TMA1221645 | SIMPLE.LIFE APPS, INC. | 9 Electronics | Registered | 2024 |
| Simpla 2188562 · TMA1232720 | Simpla Foods Inc. | 29 Meat30 Coffee | Registered | 2024 |
| SNAPFLO 2150404 · TMA1167257 | KOHLER CO. | 11 Lighting | Registered | 2023 |
| SIMPL3 2103611 · TMA1185090 | Owner not shown | 32 Beer33 Wine | Registered | 2023 |
| SIMPLY 1931811 · TMA1190191 · design | Frito-Lay North America, Inc. | 29 Meat30 Coffee | Registered | 2023 |
| SIMPLE 1894715 · TMA1093561 · design | LOBLAWS INC. | 29 Meat30 Coffee32 Beer | Registered | 2021 |
| Simply 1879346 · TMA1104013 | Simply Gum Inc | 30 Coffee | Registered | 2021 |
| SIMPLOT 1862550 · TMA1021155 · design | J.R. SIMPLOT COMPANY | 1 Chemicals29 Meat30 Coffee | Registered | 2019 |
| SIMPLOT 1862545 · TMA1021154 · design | J.R. SIMPLOT COMPANY | 1 Chemicals29 Meat30 Coffee | Registered | 2019 |
| SIMPLI 1859385 · TMA1027744 | Drylock Technologies N.V. naamloze vennootschap (abbreviation N.V.), a Belgian public limited company | 5 Pharmaceuticals | Registered | 2019 |
| SIMPLOT 1787415 · TMA995071 | J.R. SIMPLOT COMPANY | 1 Chemicals29 Meat30 Coffee | Registered | 2018 |
| SIMPLE 1769564 · TMA1025929 · design | DANONE INC. | 29 Meat | Registered | 2019 |
| SIMPLE 1708779 · TMA1045096 · design | The PNC Financial Services Group Inc. | 35 Advertising36 Finance42 Science | Registered | 2019 |
| SIMPLE 1708774 · TMA1045095 | The PNC Financial Services Group Inc. | 35 Advertising36 Finance42 Science | Registered | 2019 |
| SIMPLR 1690880 · TMA966575 | Cloud Software Group, Inc. | 42 Science | Registered | 2017 |
| SIMPL 1686686 · TMA931063 | Amenity Holdings Inc. | 9 Electronics10 Medical16 Paper+3 | Registered | 2016 |