| "SPANSULES" 0215138 · UCA41347 | GlaxoSmithKline Inc. | 5 Pharmaceuticals | Registered | 1952 |
| SPANGLE 1654563 · TMA924019 | Universal Yarn, Inc. a North Carolina corporation | 23 Yarns | Registered | 2015 |
| SPANGLE 0632448 · TMA368270 | 3M Company (a Delaware corporation) | 3 Cosmetics | Registered | 1990 |
| SPANSIVE 1976591 | Pi Inc. | 9 Electronics35 Advertising42 Science | Pending | 2019 |
| SPANSPACE 2134111 · TMA1208579 · design | DELI GROUP CO. LTD. | 9 Electronics16 Paper20 Furniture | Registered | 2023 |
| SPANXSCULPT 2368213 | Spanx, LLC | 25 Clothing | Pending | 2024 |
| SPENSALL 1974591 · TMA1155913 | Fastenal IP Company | 6 Metal35 Advertising40 Treatment | Registered | 2022 |
| SPANGLER 0873686 · TMA516880 · design | Spangler Candy Company | 30 Coffee | Registered | 1999 |
| SPANGLER 0697405 · TMA428094 | Spangler Candy Company | 30 Coffee | Registered | 1994 |
| SPANSET 0279879 · TMA139876 | an individual | 7 Machines10 Medical | Registered | 1965 |
| SPINESUITE 1364728 · TMA831531 | STRYKER CORPORATION | 9 Electronics10 Medical11 Lighting | Registered | 2012 |
| SPANXSHAPE 2368223 | Spanx, LLC | 25 Clothing | Pending | 2024 |
| SPONSORPULSE 1940378 · TMA1140120 | IMI International-Research Inc. | 35 Advertising | Registered | 2022 |
| SPINSENSE 1308120 · TMA732460 | LG ELECTRONICS INC. | 7 Machines11 Lighting | Registered | 2009 |
| SPANCRETE 0256014 · TMA120802 | The Spancrete Group, Inc. | 19 Building | Registered | 1961 |
| SPONSORME 2121199 | Clover8 Investments Pte. Ltd. | 9 Electronics10 Medical25 Clothing+5 | Pending | 2021 |
| SOBANKABLE 2190840 · TMA1234668 | Caplink Mortgage Corporation | 36 Finance | Registered | 2024 |
| SPONSIFI 2102938 · TMA1175013 | CONNECTIONPOINT SYSTEMS INC. | 35 Advertising36 Finance42 Science | Registered | 2023 |
| SPANESI 1927585 · TMA1171825 | an individual | 6 Metal7 Machines9 Electronics+2 | Registered | 2023 |
| Spank 1869359 · TMA1146258 | an individual | 3 Cosmetics5 Pharmaceuticals8 Hand+12 | Registered | 2022 |
| SpinSeal 1832577 · TMA1014440 | Gestion Capital CDL inc. | 7 Machines17 Rubber | Registered | 2019 |
| SPONGIE 1660499 · TMA914197 · design | Kruger Products Inc. | 35 Advertising41 Education | Registered | 2015 |
| SPONGIE 1659932 · TMA918063 | Kruger Products Inc. | 35 Advertising41 Education | Registered | 2015 |
| SPENCORE 1472417 · TMA800833 | Implus Footcare, LLC | 17 Rubber | Registered | 2011 |
| SPINCORE 1438685 · TMA824566 | an individual | 9 Electronics10 Medical14 Jewellery+5 | Registered | 2012 |