| SPEXI 1869940 · TMA1086266 | Spexi Geospatial Inc. | 9 Electronics42 Science | Registered | 2020 |
| Spyzie 1914492 · TMA1098968 | Shenzhen Wondershare Software Co. Ltd. | 9 Electronics | Registered | 2021 |
| SPEX 2176698 · TMA1226272 | LITELINE CORPORATION | 9 Electronics11 Lighting | Registered | 2024 |
| SPAZA 2143410 · TMA1228849 | an individual | 6 Metal16 Paper20 Furniture+1 | Registered | 2024 |
| SPEX 2133631 · TMA1240957 | an individual | 12 Vehicles | Registered | 2024 |
| SPES 2004304 · TMA1107544 | FITES | 7 Machines12 Vehicles | Registered | 2021 |
| SPEC4 2003373 · TMA1106550 | Evonik Oxeno GmbH & Co. KG | 1 Chemicals4 Oils | Registered | 2021 |
| SPEK 1984422 · TMA1247715 | American Defense Manufacturing, LLC | 9 Electronics | Registered | 2024 |
| SPEXA 1921074 · TMA1096638 | Zoetis Services LLC | 5 Pharmaceuticals | Registered | 2021 |
| SPCCI 1880265 · TMA1075920 | MAZDA MOTOR CORPORATION | 7 Machines12 Vehicles | Registered | 2020 |
| SPEX 1880116 · TMA1082640 · design | Owner not shown | 10 Medical12 Vehicles | Registered | 2020 |
| SPEQ 1860131 · TMA1055731 | Amerlux, LLC | 11 Lighting | Registered | 2019 |
| SPEKA 1854297 · TMA1052897 | an individual | 19 Building27 Carpets | Registered | 2019 |
| SPEKS 1847492 · TMA1136047 | Retrospective Goods, LLC | 9 Electronics28 Toys | Registered | 2022 |
| SPECS 1824403 · TMA1008478 | Snap Inc. | 9 Electronics | Registered | 2018 |
| SPECK 1782380 · TMA1027040 | Speculative Product Design, LLC | 9 Electronics18 Leather | Registered | 2019 |
| SPEX 1774582 · TMA1055783 | MSI Holdings, LLC | 1 Chemicals5 Pharmaceuticals9 Electronics+2 | Registered | 2019 |
| SPEAC 1717547 · TMA1054493 | Brain Sentinel, Inc. | 9 Electronics10 Medical | Registered | 2019 |
| SPEX 1609042 · TMA1000972 | Elizabeth Jocelyn Mascull and Roger Thomas Mascull as Trustees for the RT and EJ Family Trust | 10 Medical12 Vehicles | Registered | 2018 |
| SPEX 1578660 · TMA872958 | MSI Holdings, LLC | 1 Chemicals9 Electronics | Registered | 2014 |
| (*) SPECK 1519715 · TMA829409 · design | Speculative Product Design, LLC | 18 Leather | Registered | 2012 |
| (*) SPECK 1461977 · TMA776060 · design | Speculative Product Design, LLC | 9 Electronics | Registered | 2010 |
| SPECK 1461970 · TMA774353 | Speculative Product Design, LLC | 9 Electronics | Registered | 2010 |
| SPOGI 1426857 · TMA812039 | an individual | 25 Clothing | Registered | 2011 |
| SPGI 1405263 · TMA749937 · design | 9103-8794 Québec Inc. | 35 Advertising | Registered | 2009 |