| SPOMATIC 0336131 · TMA178954 | Equipment Manufacturers International, Inc. | 7 Machines | Registered | 1971 |
| Spinnator 2021732 · TMA1140431 | Triple A Finance GmbH & Co. KG | 10 Medical | Registered | 2022 |
| SAFEMATIC 0744387 · TMA444001 | an individual | 6 Metal7 Machines9 Electronics+2 | Registered | 1995 |
| Seventomatic 1873851 · TMA1095559 | an individual | 7 Machines9 Electronics12 Vehicles+1 | Registered | 2021 |
| SkyViewMatic 1441003 · TMA794756 | Owner not shown | 12 Vehicles | Registered | 2011 |
| SPONTAGI 2134040 · TMA1175992 | an individual | 5 Pharmaceuticals | Registered | 2023 |
| SPINTEK 1907467 · TMA1113232 | ORMCO CORPORATION | 10 Medical | Registered | 2021 |
| SPINTECH 1868320 · TMA1041909 | Hayward Industries, Inc. | 7 Machines | Registered | 2019 |
| SPINTALES 1824053 · TMA1086778 · design | WELSPUN INDIA LIMITED, LIMITED COMPANY | 9 Electronics10 Medical11 Lighting+5 | Registered | 2020 |
| SPINDOTV 1690560 · TMA988758 | Spin Master Ltd. | 9 Electronics35 Advertising38 Telecommunications+2 | Registered | 2018 |
| SPAMETICS 1273244 · TMA727601 | SpaMedica Infinite Vitality Clinic Yorkville Inc. | 3 Cosmetics | Registered | 2008 |
| SPINTEK 1135944 · TMA607529 | SpinTek Filtration, Inc. | 11 Lighting19 Building | Registered | 2004 |
| SHIPMATE 0992594 · NFLD2594 | UNITED NAIL AND FOUNDRY COMPANY LIMITED | 4 Oils11 Lighting19 Building+2 | Registered | 1945 |
| SHIPMATE 0990933 · NFLD933 | UNILEVER PLC | 29 Meat30 Coffee | Registered | 1920 |
| SPINET 0990745 · NFLD745 | R. & J. HILL LIMITED | 34 Tobacco | Registered | 1919 |
| SPONTIN 0236830 · TMA106326 | BGP Pharma ULC | 5 Pharmaceuticals | Registered | 1957 |
| SPINTEX 0210367 · UCA37670 | JOHNS MANVILLE CANADA INC. | 17 Rubber | Registered | 1951 |
| SPENDAI 2375044 | SpendAI, Inc. | – | Pending | 2025 |
| SHIPMATE 2177985 | Solar Sailor Pty Ltd | 12 Vehicles | Pending | 2022 |
| SOFANTASTIC 1545354 · TMA859274 | T.I.C.C. LIMITED | 35 Advertising | Registered | 2013 |
| 9SEVENTY 2277530 · TMA1267548 | New Era Cap, LLC | 25 Clothing | Registered | 2024 |
| SPINDL 2251932 · TMA1270174 | Red Thread Innovations Inc. | 42 Science | Registered | 2024 |
| SoFound 2237844 · TMA1258255 | an individual | 9 Electronics35 Advertising42 Science | Registered | 2024 |
| SEVEN9THIRTEEN 2228953 · TMA1252862 | an individual | 14 Jewellery25 Clothing35 Advertising | Registered | 2024 |
| Skybender 2223278 · TMA1280905 | 9478-9450 Québec inc. | 8 Hand | Registered | 2025 |