| STEAVAL 0641550 · TMA375919 | Phillips 66 Company | 4 Oils | Registered | 1990 |
| STIFEL 2276234 | Stifel Nicolaus Canada Inc. | 36 Finance | Pending | 2023 |
| STIPPLE 1535599 · TMA839362 | STIPPLE, INC. | 9 Electronics35 Advertising42 Science | Registered | 2013 |
| STIEFEL 0222568 · UCA48420 | Stiefel Laboratories, Inc. (a Delaware corporation) | 3 Cosmetics | Registered | 1953 |
| STIEFEL 1948615 | Stiefel Laboratories, Inc. | 5 Pharmaceuticals | Pending | 2019 |
| STOWFLEX 2207588 · TMA1242760 | General Motors LLC | 12 Vehicles | Registered | 2024 |
| SKATEFLASH 2201112 · TMA1238637 · design | an individual | 12 Vehicles | Registered | 2024 |
| SUITEFLOW 2198095 · TMA1222510 | NetSuite Inc. | 42 Science | Registered | 2024 |
| STABILIZER 2151528 · TMA1206305 | Leachman Cattle of Colorado, LLC | 5 Pharmaceuticals31 Fresh | Registered | 2023 |
| STABILITY 2119865 · TMA1208461 | WILBUR-ELLIS COMPANY OF CANADA LIMITED | 1 Chemicals | Registered | 2023 |
| SWEATFLEECE 2109405 · TMA1277260 | Aritzia LP | 25 Clothing35 Advertising | Registered | 2024 |
| SWEETPLUCK 2107899 · TMA1177733 | an individual | 30 Coffee | Registered | 2023 |
| Sodaflo 2090640 · TMA1147105 | Sodaflo Limited | 37 Construction | Registered | 2022 |
| STOPLESS 2071143 · TMA1284019 | Stopless Inc. | 9 Electronics42 Science | Registered | 2025 |
| SEEDPLATE 2051883 · TMA1278353 | Coinkite Inc. | 6 Metal | Registered | 2024 |
| SIDEFEEL 2046776 · TMA1205774 · design | Fujian New Shiying ClothingINDUSTRIAL Co., Ltd. | 25 Clothing | Registered | 2023 |
| StepLens 2032129 · TMA1268019 | Eclairage Axis Inc. | 11 Lighting | Registered | 2024 |
| STABLEVISC 2019083 · TMA1198479 | Bausch + Lomb Ireland Limited | 5 Pharmaceuticals | Registered | 2023 |
| STABLERV 2015114 · TMA1157012 | NORBORD INC. | 19 Building | Registered | 2022 |
| StufFlap 1996135 · TMA1125075 | an individual | 18 Leather | Registered | 2022 |
| StablePlas 1995811 · TMA1102984 | Cellphire, Inc. | 5 Pharmaceuticals | Registered | 2021 |
| Sodaflo 1993600 · TMA1158683 | Sodaflo Limited | 7 Machines32 Beer | Registered | 2023 |
| STABLEFIZZ 1991196 · TMA1223470 | ISP Investments LLC | 1 Chemicals | Registered | 2024 |
| STABLEPLATE 1953120 · TMA1106972 | Cellphire, Inc. | 5 Pharmaceuticals | Registered | 2021 |
| SUITABILITYPRO 1922084 · TMA1113971 | MORNINGSTAR, INC. | 9 Electronics36 Finance42 Science | Registered | 2021 |