| SAVANTA 1980686 · TMA1102570 | Next Fifteen Communications Group PLC | 35 Advertising | Registered | 2021 |
| SAFENET 1558062 · TMA836552 | THALES DIS CPL USA, INC. | 42 Science | Registered | 2012 |
| SUVANT 1404520 · TMA800982 | an individual | 18 Leather24 Textiles25 Clothing | Registered | 2011 |
| SUVANT 1404518 · TMA800983 · design | an individual | 18 Leather24 Textiles25 Clothing | Registered | 2011 |
| SEVENTY 1234574 · TMA700398 · design | an individual | 9 Electronics14 Jewellery18 Leather+4 | Registered | 2007 |
| SAFENET 1212863 · TMA669710 | THALES DIS CPL USA, INC. | 9 Electronics | Registered | 2006 |
| SAFENET 1212862 · TMA759814 · design | THALES DIS CPL USA, INC. | 9 Electronics | Registered | 2010 |
| SAFENET 0647497 · TMA376973 · design | TELUS Corporation | 9 Electronics | Registered | 1990 |
| SEVENTY 0616541 · TMA370622 · design | an individual | 25 Clothing | Registered | 1990 |
| 9SEVENTY 2277530 · TMA1267548 | New Era Cap, LLC | 25 Clothing | Registered | 2024 |
| SPINDL 2251932 · TMA1270174 | Red Thread Innovations Inc. | 42 Science | Registered | 2024 |
| SoFound 2237844 · TMA1258255 | an individual | 9 Electronics35 Advertising42 Science | Registered | 2024 |
| SEVEN9THIRTEEN 2228953 · TMA1252862 | an individual | 14 Jewellery25 Clothing35 Advertising | Registered | 2024 |
| Skybender 2223278 · TMA1280905 | 9478-9450 Québec inc. | 8 Hand | Registered | 2025 |
| SAFANAD 2218163 · TMA1257887 | Safanad Limited | 36 Finance | Registered | 2024 |
| Spoontainable 2186592 · TMA1275870 | Spoontainable GmbH | 8 Hand30 Coffee | Registered | 2024 |
| SAFinity 2180414 · TMA1211343 | ROLLS-ROYCE plc | 9 Electronics35 Advertising | Registered | 2023 |
| SUPANOTCH 2179262 · TMA1275834 | an individual | 35 Advertising41 Education | Registered | 2024 |
| 2SEVENTYBIO 7 2179212 · TMA1239647 · design | 2seventy bio, Inc. | 5 Pharmaceuticals42 Science | Registered | 2024 |
| 2SEVENTYBIO 7 2176306 · TMA1239641 · design | 2seventy bio, Inc. | 5 Pharmaceuticals42 Science | Registered | 2024 |
| SAFANAD 2170299 · TMA1284366 · design | Safanad Limited | 36 Finance | Registered | 2025 |
| SWAPNOTE 2162431 · TMA1205419 | NINTENDO OF AMERICA INC. | 9 Electronics | Registered | 2023 |
| SPONDSOPH 2156774 · TMA1208785 | an individual | 28 Toys | Registered | 2023 |
| SAPIENTCELL 2154736 · TMA1239575 | BioSentinel, Inc. | 1 Chemicals5 Pharmaceuticals | Registered | 2024 |
| SEVENTYSEVEN 2153651 · TMA1206480 | Retail Royalty Company, a Nevada, U.S.A. corporation | 3 Cosmetics | Registered | 2023 |